User profiles for Chih-Liang Chin
Chih-Liang ChinMerck Verified email at merck.com Cited by 2085 |
MRI diffusion coefficients in spinal cord correlate with axon morphometry
Following spinal cord injury, diffusion MRI (DWI) has been shown to detect injury and
functionally significant neuroprotection following treatment that otherwise would go undetected …
functionally significant neuroprotection following treatment that otherwise would go undetected …
BirdcageBuilder: design of specified‐geometry birdcage coils with desired current pattern and resonant frequency
CL Chin, CM Collins, S Li… - Concepts in Magnetic …, 2002 - Wiley Online Library
A simple method for birdcage coil design (high pass, low pass, and band pass) is presented.
Rather than iteratively approaching the Larmor resonant frequency with known …
Rather than iteratively approaching the Larmor resonant frequency with known …
[HTML][HTML] CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Non-alcoholic fatty liver disease (NAFLD) has been on a global rise. While animal models
have rendered valuable insights to the pathogenesis of NAFLD, discrepancy with patient data …
have rendered valuable insights to the pathogenesis of NAFLD, discrepancy with patient data …
[HTML][HTML] Default-mode-like network activation in awake rodents
During wakefulness and in absence of performing tasks or sensory processing, the default-mode
network (DMN), an intrinsic central nervous system (CNS) network, is in an active state. …
network (DMN), an intrinsic central nervous system (CNS) network, is in an active state. …
Biexponential diffusion attenuation in the rat spinal cord: computer simulations based on anatomic images of axonal architecture
Water diffusion in neurological tissues is known to possess multicomponent diffusion behavior.
The fractions of fast and slow apparent diffusion components have often been attributed …
The fractions of fast and slow apparent diffusion components have often been attributed …
An image‐based finite difference model for simulating restricted diffusion
Water diffusion in tissues is generally restricted and often anisotropic. Neural tissue is of
particular interest, since it is well known that injury alters diffusion in a characteristic manner. …
particular interest, since it is well known that injury alters diffusion in a characteristic manner. …
Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2, 2, 3, 3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4, 5-dimethyl-3H …
…, C Zhong, K Ryther, ME Gallagher, CL Chin… - … of Pharmacology and …, 2009 - ASPET
Studies demonstrating the antihyperalgesic and antiallodynic effects of cannabinoid CB 2
receptor activation have been largely derived from the use of receptor-selective ligands. Here, …
receptor activation have been largely derived from the use of receptor-selective ligands. Here, …
[HTML][HTML] Systematic evaluation of multiple qPCR platforms, NanoString and miRNA-Seq for microRNA biomarker discovery in human biofluids
…, L Zhou, R Zou, CM Khoo, ALS Chew, CL Chin… - Scientific reports, 2021 - nature.com
Aberrant miRNA expression has been associated with many diseases, and extracellular
miRNAs that circulate in the bloodstream are remarkably stable. Recently, there has been …
miRNAs that circulate in the bloodstream are remarkably stable. Recently, there has been …
Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine …
Neuroimaging techniques have been exploited to characterize the effect of N-methyl-d-aspartate
(NMDA) receptor antagonists on brain activation in humans and animals. However, …
(NMDA) receptor antagonists on brain activation in humans and animals. However, …
Apparent diffusion coefficients in spinal cord transplants and surrounding white matter correlate with degree of axonal dieback after injury in rats
ED Schwartz, CL Chin, JS Shumsky… - American journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Abnormal apparent diffusion coefficient (ADC) values in
injured spinal cord white matter and fibroblast transplants have been shown to correspond …
injured spinal cord white matter and fibroblast transplants have been shown to correspond …