CNS metastases are the most common cause of malignant brain tumours in adults. Historically,
patients with brain metastases have been excluded from most clinical trials, but their …

Diffusion-weighted magnetic resonance (MR) imaging and perfusion MR imaging are
advanced techniques that provide information not available from conventional MR imaging. In …

Despite the widespread clinical use of dynamic susceptibility contrast (DSC) MRI, DSC-MRI
methodology has not been standardized, hindering its utilization for response assessment in …

Although investigators in the imaging community have been active in developing and evaluating
quantitative imaging biomarkers (QIBs), the development and implementation of QIBs …

PURPOSE: To measure mean cerebral blood flow (CBF) in ischemic and nonischemic
territories and in low-attenuation regions in patients with acute stroke by using deconvolution-…

BACKGROUND AND PURPOSE: Compared with MR imaging, dynamic CT perfusion imaging
covers only a fraction of the whole brain. An important assumption is that CT perfusion …

BACKGROUND AND PURPOSE: Previous studies have shown that lesions in posterior
reversible encephalopathy syndrome are often isointense on diffusion-weighted MR images. We …

The demand for image-processing software for radiology applications has been increasing,
fueled by advancements in both image-acquisition and image-analysis techniques. The …

Quantitative analysis of dynamic contrast-enhanced MR imaging (DCE-MR imaging) has the
power to provide information regarding physiologic characteristics of the microvasculature …

Quantitative biomarkers from medical images are becoming important tools for clinical
diagnosis, staging, monitoring, treatment planning, and development of new therapies. While …