User profiles for D. Dowlatshahi
Dar DowlatshahiUniversity of Ottawa, Ottawa Hospital Research Institute Verified email at toh.on.ca Cited by 51310 |
2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke …
… Dar Dowlatshahi … Dar Dowlatshahi Dar Dowlatshahi …
[HTML][HTML] Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data
…, L Masotti, D Dowlatshahi, D Rodriguez-Luna… - The Lancet …, 2018 - thelancet.com
Background Intracerebral haemorrhage growth is associated with poor clinical outcome and
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …
Intracerebral haemorrhage
…, AR Parry-Jones, EC Sandset, D Dowlatshahi… - Nature Reviews …, 2023 - nature.com
… observed in cerebral amyloid angiopathy and used in the Boston criteria version 2.0: cortical
superficial siderosis (panel c), white-matter hyperintensities with multispot pattern (panel d) …
superficial siderosis (panel c), white-matter hyperintensities with multispot pattern (panel d) …
[HTML][HTML] Randomized assessment of rapid endovascular treatment of ischemic stroke
…, BL Sapkota, D Dowlatshahi… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …
to 80% of patients die within 90 days after stroke onset or do not regain functional …
Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
B Chen, D Dowlatshahi, GM MacQueen, JF Wang… - Biological …, 2001 - Elsevier
Background: The cAMP signaling pathway, and its downstream neurotrophic factor BDNF,
are major targets of antidepressant medications. Abnormalities in this pathway have …
are major targets of antidepressant medications. Abnormalities in this pathway have …
[HTML][HTML] An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
… This restriction in bacterial intake significantly increased worm lifespan (Figure 1C; Table
S1 in the Supplemental Data available online) and reduced worm mortality rate (Figure 1D), …
S1 in the Supplemental Data available online) and reduced worm mortality rate (Figure 1D), …
Canadian stroke best practice recommendations: stroke rehabilitation practice guidelines, update 2015
Stroke rehabilitation is a progressive, dynamic, goal-orientated process aimed at enabling a
person with impairment to reach their optimal physical, cognitive, emotional, communicative, …
person with impairment to reach their optimal physical, cognitive, emotional, communicative, …
Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational …
…, D Dowlatshahi, D Rodriguez-Luna… - The Lancet …, 2012 - thelancet.com
Background In patients with intracerebral haemorrhage (ICH), early haemorrhage expansion
affects clinical outcome. Haemostatic treatment reduces haematoma expansion, but fails to …
affects clinical outcome. Haemostatic treatment reduces haematoma expansion, but fails to …
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …
…, G Gubitz, A Tkach, L Catanese, D Dowlatshahi… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …