Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with
vasculitis, affecting predominantly medium-sized arteries, particularly the coronary arteries. In …

… : expert opinion; SoR: strength of recommendation; A: based on level 1 evidence; B: based
on level 2 or extrapolated from level 1; C: based on level 3 or extrapolated from level 1 or 2; D…

Medium-size-artery vasculitides do occur in childhood and manifest, in the main, as polyarteritis
nodosa (PAN), cutaneous PAN and Kawasaki disease. Of these, PAN is the most serious…

… PhD Fellowship for Dr D Eleftheriou. 1/8/09-31/7/2012 5. Arthritis Research UK. … Eleftheriou
has received funding from Arthritis Research UK. P. Brogan has received consultancy fees …

The mechanisms by which anti-neutrophil cytoplasmic antibodies (ANCAs) may contribute to
the pathogenesis of ANCA-associated vasculitis are not well understood. In this study, both …

… The strength of each statement ranged from A (directly based on level I evidence) to D (directly
based on level IV evidence or extrapolated recommendations from level I, II, or III …

… Renovascular involvement was present in 3 subjects (subjects D, E, and F), with renal
arterial aneurysms and other features of medium vessel vasculitis demonstrated on catheter …

Background Rare chronic childhood vasculitides lack a reliable disease activity assessment
tool. With emerging new treatment modalities such a tool has become increasingly essential …

… 5 D), suggesting that the phagocytic defect may not affect all phagocytic cell types to the same
extent… 3 D) similar to those we observed in the patient moDCs (Fig.3B). We then studied co-…

Objective Polyarteritis nodosa (PAN) is a rare disease of childhood. The aims of this study
were to describe the clinical features, treatment, and outcome of systemic childhood PAN and …