The effect of genotype on the natural history of eIF2B-related leukodystrophies

…, R Surtees, D Pugin, MP Chaunu, D Rodriguez… - Neurology, 2004 - AAN Enterprises
Background: Recessive mutations in the five eucaryotic initiation factor 2B (eIF2B) subunits
have been found in leukodystrophies of variable age at onset and severity. Objectives: To …

Seizure burden in subarachnoid hemorrhage associated with functional and cognitive outcome

GM De Marchis, D Pugin, E Meyers, A Velasquez… - Neurology, 2016 - AAN Enterprises
… Deborah Pugin: acquisition of data, analysis and interpretation of data, critical revision of
the manuscript for important intellectual content. Emma Meyers: acquisition of data, analysis …

A risk analysis method to evaluate the impact of a computerized provider order entry system on patient safety

…, P Casez, M Despond, D Pugin… - Journal of the …, 2008 - academic.oup.com
Objectives: Quantitative evaluation of safety after the implementation of a computerized
provider order entry (CPOE) system, stratification of residual risks to drive future developments. …

Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome

…, JM Schmidt, GM De Marchis, D Pugin… - Annals of …, 2014 - Wiley Online Library
Objective Nonconvulsive seizures (NCSz) are frequent following acute brain injury and have
been implicated as a cause of secondary brain injury, but mechanisms that cause NCSz …

COVID-19–related encephalopathy responsive to high-dose glucocorticoids

D Pugin, MI Vargas, C Thieffry, M Schibler… - Neurology, 2020 - AAN Enterprises
One hundred twenty patients with coronavirus disease 2019 (COVID-19) were hospitalized
in our intensive care unit, Geneva, Switzerland, between March 9 and April 16, 2020. We …

COVID‐19 is associated with an unusual pattern of brain microbleeds in critically ill patients

A Fitsiori, D Pugin, C Thieffry, P Lalive… - Journal of …, 2020 - Wiley Online Library
BACKGROUND AND PURPOSE Covid‐19, initially described as a respiratory system's
infection, is currently more and more recognized as a multiorganic disease, including …

[HTML][HTML] Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study

D Pugin, B Foreman, GM De Marchis, A Fernandez… - Critical Care, 2014 - Springer
… Another patient with N-methyl-D-aspartate receptor encephalitis developed propylene-glycol
intoxication with severe acidosis, which resolved after cessation of cIV-PTB. All patients in …

[PDF][PDF] Unusual microbleeds in brain MRI of Covid-19 patients

A Fitsiori, D Pugin, C Thieffry, P Lalive… - J Neuroimaging, 2020 - researchgate.net
BACKGROUND AND PURPOSE: Covid-19, initially described as a respiratory system’s
infection, is currently more and more recognized as a multiorganic disease, including …

[HTML][HTML] Preparedness and reorganization of care for coronavirus disease 2019 patients in a Swiss ICU: characteristics and outcomes of 129 patients

…, D Pugin, N Siegenthaler, D Tassaux… - Critical care …, 2020 - journals.lww.com
Pugin had the idea and designed the study. They had … d), but it was not significantly longer
in patients discharged alive from the ICU (median, 16 d [IQR, 11–21 d] vs 12.5 d [IQR, 9–18 d] …

Resting-state brain activity for early prediction outcome in postanoxic patients in a coma with indeterminate clinical prognosis

D Pugin, J Hofmeister, Y Gasche… - American Journal …, 2020 - Am Soc Neuroradiology
D. Pugin is funded by a research fellowship of the Faculty of Medicine of Geneva University
and by a Templin grant. J. Hofmeister is supported by a Research and Development fund by …