User profiles for D.A. Wolk
Dave WolkProfessor of Neurology, University of Pennsylvania Verified email at uphs.upenn.edu Cited by 22165 |
Vascular disease and dementias: paradigm shifts to drive research in new directions
Vascular disease was once considered the principal cause of aging-related dementia. More
recently, however, research emphasis has shifted to studies of progressive …
recently, however, research emphasis has shifted to studies of progressive …
Arterial spin labeling MRI: an emerging biomarker for Alzheimer's disease and other neurodegenerative conditions
ASL MRI is just beginning to be applied more widely to various neurodegenerative conditions.
Initial data suggest that this methodology may provide similar information to FDG PET, but …
Initial data suggest that this methodology may provide similar information to FDG PET, but …
The National Institute on Aging and the Alzheimer's Association research framework for Alzheimer's disease: perspectives from the research roundtable
…, SM Resnick, G Romano, AC van Harten, DA Wolk… - Alzheimer's & …, 2018 - Elsevier
The Alzheimer's Association's Research Roundtable met in November 2017 to explore the
new National Institute on Aging and the Alzheimer's Association Research Framework for …
new National Institute on Aging and the Alzheimer's Association Research Framework for …
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
…, G Waldemar, A Wallin, ÅK Wallin, J Wiltfang, DA Wolk… - Jama, 2015 - jamanetwork.com
Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
…, KS Frederiksen, AS Fleisher, MA Mintun, DA Wolk… - Jama, 2015 - jamanetwork.com
… Dr Wolk reports consulting for GE Healthcare and being a site private investigator for a clinical
trial supported by AVID/Lilly. Dr Rinne reports receiving grant funding from Sigrid Juselius …
trial supported by AVID/Lilly. Dr Rinne reports receiving grant funding from Sigrid Juselius …
Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment
We evaluate a fully automatic technique for labeling hippocampal subfields and cortical
subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs …
subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs …
Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging
Background The aim of this study was to compare the utility and diagnostic accuracy of the
Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) in the …
Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) in the …
Amyloid imaging in mild cognitive impairment subtypes
Objective We utilized the amyloid imaging ligand Pittsburgh Compound B (PiB) to determine
the presence of Alzheimer's disease (AD) pathology in different mild cognitive impairment (…
the presence of Alzheimer's disease (AD) pathology in different mild cognitive impairment (…
Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease
Background: Patients using cholinesterase inhibitors (ChEIs) have a delay in nursing home (NH)
admission compared with those who were not using the medication. There are no long-…
admission compared with those who were not using the medication. There are no long-…
[HTML][HTML] Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan
…, MS Albert, HJ Grabe, SM Resnick, RN Bryan, DA Wolk… - NeuroImage, 2020 - Elsevier
As medical imaging enters its information era and presents rapidly increasing needs for big
data analytics, robust pooling and harmonization of imaging data across diverse cohorts with …
data analytics, robust pooling and harmonization of imaging data across diverse cohorts with …