User profiles for D.B. Orbach

Darren Orbach

Boston Children's Hospital
Verified email at childrens.harvard.edu
Cited by 3847

PHACE syndrome: consensus-derived diagnosis and care recommendations

…, GL Heyer, PC Frommelt, DB Orbach… - The Journal of …, 2016 - jpeds.com
Methods The development of the content followed the customary consensus methodology
based on a comprehensive review of published data and on the experience of a …

Retinoblastoma

C Rodriguez-Galindo, DB Orbach… - Pediatric …, 2015 - pediatric.theclinics.com
Retinoblastoma is the most common neoplasm of the eye in childhood, representing 2.5%
to 4% of all pediatric cancers. The average age-adjusted incidence rate of retinoblastoma in …

Management of arteriovenous malformations

AK Greene, DB Orbach - Clinics in plastic surgery, 2011 - plasticsurgery.theclinics.com
Arteriovenous malformation (AVM) results from an error in vascular development during
embryogenesis. An absent capillary bed causes shunting of blood directly from the arterial to …

Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders

SA Morris, DB Orbach, T Geva, MN Singh… - Circulation, 2011 - Am Heart Assoc
… Patients were identified by a search of the computer database of the Cardiovascular Program
at Children's Hospital Boston using the following criteria: (1) Age ≤50 years with MS, LDS, …

Optimizing cerebrovascular surgical and endovascular procedures in children via personalized 3D printing

P Weinstock, SP Prabhu, K Flynn, DB Orbach… - Journal of Neurosurgery …, 2015 - thejns.org
OBJECT Despite the availability of multiplanar imaging, understanding relational 3D
anatomy for complex cerebrovascular lesions can be difficult. A 3D printed model allows for …

The natural history of cerebral cavernous malformations in children

BA Gross, R Du, DB Orbach, RM Scott… - Journal of Neurosurgery …, 2016 - thejns.org
OBJECT Cerebral cavernous malformations (CMs) are a source of neurological morbidity
from seizures and focal neurological deficits due to mass effect and hemorrhage. Although …

Microsurgical treatment of arteriovenous malformations in pediatric patients: the Boston Children's Hospital experience

BA Gross, A Storey, DB Orbach, RM Scott… - Journal of Neurosurgery …, 2015 - thejns.org
OBJECT Outcomes of microsurgical treatment of arteriovenous malformations (AVMs) in
children are infrequently reported across large cohorts. METHODS The authors undertook a …

Endovascular therapy in children with acute ischemic stroke: review and recommendations

MJ Ellis, C Amlie-Lefond, DB Orbach - Neurology, 2012 - AAN Enterprises
This review provides a summary of the currently available data pertaining to the interventional
management of acute ischemic stroke in children. The literature is scarce and is lacking …

[PDF][PDF] Mutations in chromatin modifier and ephrin signaling genes in vein of Galen malformation

…, G Rodesch, E Jackson, ER Smith, DB Orbach… - Neuron, 2019 - cell.com
… Chromatin genes used for analysis were extracted from the Biomart database using GO:…
MAF % 2 3 10À5 in the Genome Aggregation database (gnomAD) in LoFintolerant genes (pLI R …

A novel association between RASA1 mutations and spinal arteriovenous anomalies

…, ER Smith, M Vikkula, DB Orbach - American journal …, 2010 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: CM-AVM is a recently recognized autosomal dominant
disorder associated with mutations in RASA1. Arteriovenous lesions have been reported in the …