Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …

After completion of this article, the reader will be able to 1) state the therapeutic interventions
that are currently used to treat intraocular retinoblastoma, and to outline the mechanism of …

The management of intraocular retinoblastoma is rapidly changing, and even recent
reviews on the subject are behind existing practices. The 4 authors of this report collectively …

Context. —There is a substantial risk of a second cancer for persons with hereditary
retinoblastoma, which is enhanced by radiotherapy. Objective. —To examine long-term risk of new …

Background: Children diagnosed with retinoblastoma, a rare cancer of the eye, tend to develop
and die of second primary cancers in childhood and adolescence, but few investigations …

Importance Uveal melanoma is characterized by mutations inGNAQandGNA11, resulting in
mitogen-activated protein kinase pathway activation. Objective To assess the efficacy of …

OBJECTIVE: To develop a technique that would allow us to cannulate repeatedly the ophthalmic
artery of young children with advanced retinoblastoma, to find a dose of melphalan that …

… Eng C, Li FP, Abramson DH, et al: Mortality from second tumors among long-term survivors …
Kleinerman RA, Tarone RE, Abramson DH, et al: Hereditary retinoblastoma and risk of lung …

… DH Spontaneously resolving periocular erythema and ciliary madarosis following intra-…
DH Spontaneously resolving periocular erythema and ciliary madarosis following intra-arterial …

A review of 693 patients with bilateral retinoblastoma and 18 patients with unilateral/germinal
retinoblastoma was carried out to find the incidence, time, course and pattern of second …