User profiles for D.M. Johnstone
Daniel M JohnstoneUniversity of Sydney Verified email at sydney.edu.au Cited by 2957 |
Intracranial arterial wall imaging using high-resolution 3-tesla contrast-enhanced MRI
…, J Butany, BA Wasserman, DM Johnstone… - Neurology, 2009 - AAN Enterprises
Background: Conventional arterial imaging focuses on the vessel lumen but lacks specificity
because different pathologies produce similar luminal defects. Wall imaging can …
because different pathologies produce similar luminal defects. Wall imaging can …
[HTML][HTML] Turning on lights to stop neurodegeneration: the potential of near infrared light therapy in Alzheimer's and Parkinson's disease
Alzheimer's and Parkinson's disease are the two most common neurodegenerative disorders.
They develop after a progressive death of many neurons in the brain. Although therapies …
They develop after a progressive death of many neurons in the brain. Although therapies …
[HTML][HTML] Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex–evidence from two transgenic mouse models
S Purushothuman, DM Johnstone… - Alzheimer's research & …, 2014 - Springer
Introduction Previous work has demonstrated the efficacy of irradiating tissue with red to
infrared light in mitigating cerebral pathology and degeneration in animal models of stroke, …
infrared light in mitigating cerebral pathology and degeneration in animal models of stroke, …
Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism–an abscopal neuroprotective effect
DM Johnstone, N El Massri, C Moro, S Spana… - Neuroscience, 2014 - Elsevier
We have previously shown near infrared light (NIr), directed transcranially, mitigates the loss
of dopaminergic cells in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-treated mice, …
of dopaminergic cells in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-treated mice, …
The mechanical cause of age-related dementia (Alzheimer's disease): the brain is destroyed by the pulse
This review traces evidence that age-related dementia (Alzheimer's disease) results from
the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the …
the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the …
Cranial dural arteriovenous fistula: diagnosis and classification with time-resolved MR angiography at 3T
…, RA Willinsky, DM Johnstone - American journal of …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The diagnosis of dural arteriovenous fistula (DAVF)
remains one of the few uncontested indications for catheter based cerebral angiography. We …
remains one of the few uncontested indications for catheter based cerebral angiography. We …
Near‐infrared light is neuroprotective in a monkey model of P arkinson disease
…, N El Massri, C Chabrol, DM Johnstone… - Annals of …, 2016 - Wiley Online Library
Objective To examine whether near‐infrared light (NIr) treatment reduces clinical signs and/or
offers neuroprotection in a subacute 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP…
offers neuroprotection in a subacute 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP…
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
Increased iron levels and dysregulated iron homeostasis, or both, occur in several lung
diseases. Here, the effects of iron accumulation on the pathogenesis of pulmonary fibrosis and …
diseases. Here, the effects of iron accumulation on the pathogenesis of pulmonary fibrosis and …
The impact of near-infrared light on dopaminergic cell survival in a transgenic mouse model of parkinsonism
S Purushothuman, C Nandasena, DM Johnstone… - Brain research, 2013 - Elsevier
We have examined whether near-infrared light (NIr) treatment mitigates oxidative stress and
increased expression of hyperphosphorylated tau in a tau transgenic mouse strain (K3) that …
increased expression of hyperphosphorylated tau in a tau transgenic mouse strain (K3) that …
Near infrared light mitigates cerebellar pathology in transgenic mouse models of dementia
S Purushothuman, DM Johnstone, C Nandasena… - Neuroscience …, 2015 - Elsevier
We previously reported that Alzheimer-related pathology in cerebral cortex of APP/PS1 and
K3 tau transgenic mouse strains is mitigated by near infrared light (NIr). Here, we extend …
K3 tau transgenic mouse strains is mitigated by near infrared light (NIr). Here, we extend …