User profiles for D.M. Johnstone

Daniel M Johnstone

University of Sydney
Verified email at sydney.edu.au
Cited by 2957

Intracranial arterial wall imaging using high-resolution 3-tesla contrast-enhanced MRI

…, J Butany, BA Wasserman, DM Johnstone… - Neurology, 2009 - AAN Enterprises
Background: Conventional arterial imaging focuses on the vessel lumen but lacks specificity
because different pathologies produce similar luminal defects. Wall imaging can …

[HTML][HTML] Turning on lights to stop neurodegeneration: the potential of near infrared light therapy in Alzheimer's and Parkinson's disease

DM Johnstone, C Moro, J Stone, AL Benabid… - Frontiers in …, 2016 - frontiersin.org
Alzheimer's and Parkinson's disease are the two most common neurodegenerative disorders.
They develop after a progressive death of many neurons in the brain. Although therapies …

[HTML][HTML] Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex–evidence from two transgenic mouse models

S Purushothuman, DM Johnstone… - Alzheimer's research & …, 2014 - Springer
Introduction Previous work has demonstrated the efficacy of irradiating tissue with red to
infrared light in mitigating cerebral pathology and degeneration in animal models of stroke, …

Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism–an abscopal neuroprotective effect

DM Johnstone, N El Massri, C Moro, S Spana… - Neuroscience, 2014 - Elsevier
We have previously shown near infrared light (NIr), directed transcranially, mitigates the loss
of dopaminergic cells in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-treated mice, …

The mechanical cause of age-related dementia (Alzheimer's disease): the brain is destroyed by the pulse

J Stone, DM Johnstone, J Mitrofanis… - Journal of Alzheimer's …, 2015 - content.iospress.com
This review traces evidence that age-related dementia (Alzheimer's disease) results from
the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the …

Cranial dural arteriovenous fistula: diagnosis and classification with time-resolved MR angiography at 3T

…, RA Willinsky, DM Johnstone - American journal of …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The diagnosis of dural arteriovenous fistula (DAVF)
remains one of the few uncontested indications for catheter based cerebral angiography. We …

Near‐infrared light is neuroprotective in a monkey model of P arkinson disease

…, N El Massri, C Chabrol, DM Johnstone… - Annals of …, 2016 - Wiley Online Library
Objective To examine whether near‐infrared light (NIr) treatment reduces clinical signs and/or
offers neuroprotection in a subacute 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP…

Critical role for iron accumulation in the pathogenesis of fibrotic lung disease

…, BG Oliver, D Trinder, DM Johnstone… - The Journal of …, 2020 - Wiley Online Library
Increased iron levels and dysregulated iron homeostasis, or both, occur in several lung
diseases. Here, the effects of iron accumulation on the pathogenesis of pulmonary fibrosis and …

The impact of near-infrared light on dopaminergic cell survival in a transgenic mouse model of parkinsonism

S Purushothuman, C Nandasena, DM Johnstone… - Brain research, 2013 - Elsevier
We have examined whether near-infrared light (NIr) treatment mitigates oxidative stress and
increased expression of hyperphosphorylated tau in a tau transgenic mouse strain (K3) that …

Near infrared light mitigates cerebellar pathology in transgenic mouse models of dementia

S Purushothuman, DM Johnstone, C Nandasena… - Neuroscience …, 2015 - Elsevier
We previously reported that Alzheimer-related pathology in cerebral cortex of APP/PS1 and
K3 tau transgenic mouse strains is mitigated by near infrared light (NIr). Here, we extend …