OBJECTIVE: Craniopharyngiomas have traditionally represented a challenge for open
transcranial or transsphenoidal microscopic neurosurgery because of their anatomical location …

Giant (>4 cm) pituitary macroadenomas often require surgery to decompress the optic nerves.
Compared with traditional open or transsphenoidal microscopic methods, the extended …

OBJECTIVE: To assess the advantages and limitations of the endoscopic endonasal approach
to anterior skull base meningiomas, a minimally invasive approach that avoids extensive …

Context: It is unclear whether endoscopic transsphenoidal surgery (ETSS) or microsurgical
transsphenoidal surgery (MTS) is a superior surgical approach for pituitary adenomas. …

Object Atypical (WHO Grade II) meningiomas comprise a heterogeneous group of tumors,
with histopathology delineated under the guidance of the WHO and a spectrum of clinical …

Vascular smooth muscle cells (SMC) maintain significant plasticity. Following environmental
stimulation, SMC can alter their phenotype from one primarily concerned with contraction to …

Background Repair of anterior skull base cerebrospinal fluid (CSF) leaks, encephaloceles,
and meningoceles can prevent meningitis, intracranial abscess, and pneumocephalus. …

BACKGROUND AND PURPOSE: Preoperative embolization for intracranial meningiomas
offers potential advantages for safer and more effective surgery. However, this treatment …

Little data exists comparing endoscopic endonasal approaches to pathology of the anterior
skull base with more traditional transcranial and transsphenoidal microscopic approaches. In …

Object As endovascular techniques have become more advanced, preoperative embolization
has become an increasingly used intervention in the management of meningiomas. To …