BACKGROUND AND PURPOSE: Acute basilar occlusions have a poor prognosis without
recanalization. Many have underlying severe atherosclerotic intracranial stenosis coexisting …

Background and Purpose Short-term combined use of clopidogrel and aspirin improves
cerebrovascular outcomes in patients with symptomatic extracranial or intracranial stenosis. …

Purpose: Current studies on endovascular intervention for intracranial atherosclerosis select
patients based on luminal stenosis. Coronary studies demonstrated that fractional flow …

The optimal treatment of chronic middle cerebral artery (MCA) occlusion is unclear.
Angioplasty and stenting may be an alternative treatment for patients with recurrent ischemic …

Background: For patients with symptomatic intracranial artery stenosis (sICAS), endovascular
treatment has been shown to be feasible and safe in recent studies. However, in-stent …

… We have discussed the role of the central oxygen atom and the (dp)π … The (dp)π conjugation
effects play essential role in stabilizing these cluster compounds, and the reduced (dp)π …

… per million opportunities (DPMO). Applying the concept of DPMO to a healthcare context,
Sedlack et al. described that if the aviation industry operated to the 95 DPMO (5.25 sigma) level …

… metrics), these measures are converted to DPMO and then to the current Process Sigma. As
… has a DPMO of 66,000, then the 10× rule sets the improvement goal at 6600 DPMO. Use of …

… In all 267 pts, the ORR was 37.1% and median DOR (mDOR) was 11.8 mo; in pts with IHC
3+ expression, the ORR was 61.3% and mDOR was 22.1 mo. ORR per cohort is shown in all …

… These levels are expressed in terms of defects per million opportunities (DPMO). Thus, a
Sigma 2 level equates to 308,537 DPMO; a Sigma 3 level to 66,807 DPMO; a Sigma 4 level to …