Purpose of Review The chimeric antigen receptor (CAR) T-cell therapy is currently changing
the landscape of hematologic malignancies with multiple FDA-approved cell therapy …

Objectives To identify MRI biomarkers associated with long-term disability progression in
patients with multiple sclerosis (MS), and to define the rate of evolution of global, tissue-specific …

Background Cardiovascular (CV) risk factors have been associated with changes in clinical
outcomes in patients with multiple sclerosis (MS). Objectives To investigate the frequency of …

The purpose of this study was to compare the clinical and quantitative magnetic resonance
imaging metrics of paediatric-onset multiple sclerosis to adult-onset multiple sclerosis. It was …

Magnetic resonance imaging (MRI) is the most important paraclinical measure for assessing
and monitoring the pathologic changes implicated in the onset and progression of multiple …

Cortical and subcortical atrophy occurs in multiple sclerosis (MS) and relates to clinical
outcomes. FreeSurfer, a voxel-based automated software for brain reconstruction was used to …

Background: Leptomeningeal contrast enhancement (LM CE) has been recently described
in multiple sclerosis (MS) patients as a potential in vivo marker of cortical pathology. …

Background Cardiovascular diseases ( CVD s) are more frequent in multiple sclerosis ( MS
) patients when compared to controls. In particular, CVD s are linked with higher …

Background: We explored the evolution of brain atrophy in relation to development of confirmed
disability progression (CDP) on serial 1.5T magnetic resonance imaging (MRI) scans …

Background: Cognitive decline is characterized in multiple sclerosis (MS), but the rate and
severity vary. The reserve hypothesis proposes that baseline neurological differences impact …