Determining the genetic basis of cancer requires comprehensive analyses of large collections
of histopathologically well-classified primary tumours. Here we report the results of a …

Background The full complement of DNA mutations that are responsible for the pathogenesis
of acute myeloid leukemia (AML) is not yet known. Methods We used massively parallel …

Background The genetic alterations responsible for an adverse outcome in most patients
with acute myeloid leukemia (AML) are unknown. Methods Using massively parallel DNA …

Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse,
which is associated with clonal evolution at the cytogenetic level 1 , 2 . To determine the …

Cancer is a disease driven by genetic variation and mutation. Exome sequencing can be
utilized for discovering these variants and mutations across hundreds of tumors. Here we …

Large, labeled datasets have driven deep learning methods to achieve expert-level
performance on a variety of medical imaging tasks. We present CheXpert, a large dataset that …

Gratitude is conceptualized as a moral affect that is analogous to other moral emotions such
as empathy and guilt. Gratitude has 3 functions that can be conceptualized as morally …

Most mutations in cancer genomes are thought to be acquired after the initiating event,
which may cause genomic instability and drive clonal evolution. However, for acute myeloid …

Psychologists' emerging interest in spirituality and religion as well as the relevance of each
phenomenon to issues of psychological importance requires an understanding of the …

Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about
13,000 adults in the United States each year. The treatment of this disease has changed little in …