One of the great goals in neuroscience research has been to improve the recovery of the
mammalian central nervous system after damage. Considerable effort has gone into learning …

The meninges of various mammals were prepared for examination with the electronmicroscope
by thin sectioning or freeze‐fracturing. Particular attention was given to the distribution of …

The axoplasm at the presynaptic active zone of excitatory synapses between parallel fibers
and Purkinje cell spines contains a meshwork of distinct filaments intermingled with synaptic …

Background and Purpose— The objective of this study was to determine the clinical features,
angiographic findings, and response to treatment with thrombolytic therapy in patients with …

The application of freeze-fracture techniques to studies of brain structure has led to the
recognition of two unsuspected specializations of membrane structure, each distributed in a …

Plasma membranes can be split in freeze-fracture preparations, revealing details of their
internal structure (1, 2, 7, 9). The membrane faces so exposed typically are dotted with globular …

Background and Purpose— Although long-term outcome determinants in acute ischemic
stroke (AIS) patients have been defined, less is known about those predicting hyperacute …

We report here the genetic basis for a form of progressive hereditary spastic paraplegia (
SPG 43) previously described in two M alian sisters. Exome sequencing revealed a …

Postnatal development of the cerebellar cortex has been compared in staggerer mutant and
unaffected littermate mice. From postnatal day 3 to about day 21 the external granular layer …

PURPOSE: To test diffusion- and perfusion-weighted MR imaging techniques within the
extreme time constraints of stroke evaluation before therapy, and then, with MR imaging, stratify …