Evidence for axonal pathology and adaptive cortical reorganization in patients at presentation with clinically isolated syndromes suggestive of multiple sclerosis

MA Rocca, DM Mezzapesa, A Falini, A Ghezzi… - Neuroimage, 2003 - Elsevier
Previous work has suggested that functional reorganization of cortical areas might have a
role in limiting the clinical impact of axonal pathology in patients with established multiple …

Simple and complex movement‐associated functional MRI changes in patients at presentation with clinically isolated syndromes suggestive of multiple sclerosis

M Filippi, MA Rocca, DM Mezzapesa… - Human brain …, 2004 - Wiley Online Library
Using functional magnetic resonance imaging (fMRI), we investigated whether movement‐associated
functional changes of the brain are present in patients who are, most likely, at the …

Morphological analysis of the brain subcortical gray structures in restless legs syndrome

MP Mogavero, DM Mezzapesa, M Savarese… - Sleep medicine, 2021 - Elsevier
Background Although several studies have shown the involvement of specific structures of
the central nervous system, the dopaminergic system, and iron metabolism in restless legs …

Functional cortical changes of the sensorimotor network are associated with clinical recovery in multiple sclerosis

DM Mezzapesa, MA Rocca, M Rodegher… - Human brain …, 2008 - Wiley Online Library
Objective: To assess the early cortical changes following an acute motor relapse secondary
to a pseudotumoral lesion in MS patients, the longitudinal cortical functional correlates of …

A functional magnetic resonance imaging study of patients with secondary progressive multiple sclerosis

…, DM Mezzapesa, A Falini, B Colombo, M Mascalchi… - Neuroimage, 2003 - Elsevier
Although several functional magnetic resonance imaging (fMRI) studies have shown
adaptive cortical changes in patients with early multiple sclerosis (MS), the presence of brain …

fMRI changes in relapsing‐remitting multiple sclerosis patients complaining of fatigue after IFNβ‐1a injection

…, F Agosta, B Colombo, DM Mezzapesa… - Human brain …, 2007 - Wiley Online Library
If fatigue in multiple sclerosis (MS) is related to an abnormal activation of the sensorimotor
brain network, the activity of such a network should vary with varying fatigue. We studied 22 …

A functional MRI study of movement-associated cortical changes in patients with Devic's neuromyelitis optica

MA Rocca, F Agosta, DM Mezzapesa, A Falini… - Neuroimage, 2004 - Elsevier
Movement-associated cortical changes have been shown in several neurological
conditions and were found to be associated to the extent of brain and cord damage. Devic's …

Proton magnetic resonance spectroscopy in Parkinson's disease and atypical parkinsonian disorders

…, M De Mari, P Giannini, DM Mezzapesa… - Movement …, 1997 - Wiley Online Library
Proton magnetic resonance spectroscopy ( 1 H‐MRS), localized to the lentiform nucleus,
was carried out in 12 patients with idiopathic Parkinson's disease (IPD), seven patients with …

MRI quantification of gray and white matter damage in patients with early–onset multiple sclerosis

P Tortorella, MA Rocca, DM Mezzapesa, A Ghezzi… - Journal of …, 2006 - Springer
Background and objective Contrary to what happens in adult–onset multiple sclerosis (MS),
in a previous preliminary magnetic resonance imaging (MRI) study we showed only subtle …

A functional MRI study of cortical activations associated with object manipulation in patients with MS

M Filippi, MA Rocca, DM Mezzapesa, A Falini… - Neuroimage, 2004 - Elsevier
Previous functional magnetic resonance imaging (fMRI) studies of simple motor tasks have
shown that in patients with multiple sclerosis (MS), there is an increased recruitment of …