Fibrolamellar hepatocellular carcinoma in children and adolescents

…, JA Ortega, W Qu, EC Douglass… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Children with hepatocellular carcinoma (HCC) were treated on a
prospective, randomized trial and were then analyzed to determine whether children with the …

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

…, T Glaser, KM Call, J Pelletier, RL Sohn, EC Douglass… - Cell, 1990 - cell.com
We have recently described the isolation of a candidate for the Wilms’ tumor susceptibility
gene mapping to band~ 13 of human chromosome 11. This gene, primarily expressed in fetal …

Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study.

…, FA Hayes, JJ Shuster, EC Douglass… - Journal of Clinical …, 1991 - ascopubs.org
We assessed tumor cell DNA content (ploidy) and N-myc gene copy number as predictors
of long-term disease-free survival in 298 children with neuroblastoma. Diploid tumor stem …

Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor.

GR Dressler, EC Douglass - Proceedings of the National …, 1992 - National Acad Sciences
The murine Pax-2 gene contains a protein coding domain homologous to the Drosophila
paired-box, first described in certain developmental control genes of the segmentation type. …

Randomized comparison of cisplatin/vincristine/fluorouracil and cisplatin/continuous infusion doxorubicin for treatment of pediatric hepatoblastoma: a report from the …

JA Ortega, EC Douglass, JH Feusner… - Journal of clinical …, 2000 - ascopubs.org
PURPOSE: Previous studies demonstrated that chemotherapy with either cisplatin, vincristine,
and fluorouracil (regimen A) or cisplatin and continuous infusion doxorubicin (regimen B) …

A specific chromosomal abnormality in rhabdomyosarcoma

EC Douglass, M Valentine, E Etcubanas… - … and Genome Research, 1987 - karger.com
Douglass EC: In situ selection of a human rhabdomyosarcoma resistant to vincristine with
altered beta tubulin. Cancer Res 45:2706-2712 (1985). Houghton JA, Houghton PJ, Webber …

Chromosome translocation in peripheral neuroepithelioma

…, T Knutsen, J Miser, EC Douglass… - … England Journal of …, 1984 - Mass Medical Soc
PERIPHERAL neuroepithelioma (peripheral neuroblastoma) is an uncommon malignant
tumor of the peripheral nervous system with a histologic appearance similar to that of classical …

There is no role for hyperfractionated radiotherapy in the management of children with newly diagnosed diffuse intrinsic brainstem tumors: results of a Pediatric …

…, R Kadota, C Freeman, EC Douglass… - International Journal of …, 1999 - Elsevier
Purpose: In June 1992, POG began accrual to a phase III study, POG-9239, designed to
compare the time to disease progression, overall survival, and toxicities observed in children …

Amplification of the gli Gene in Childhood Sarcomas

WM Roberts, EC Douglass, SC Peiper, PJ Houghton… - Cancer research, 1989 - AACR
The gli gene, originally identified by its amplified copy number in cells from a human malignant
glioma, has a predicted translation product that contains five tandem DNA-binding zinc …

Hepatocellular carcinoma in children and adolescents: results from the Pediatric Oncology Group and the Children's Cancer Group intergroup study

…, JA Ortega, W Liu-Mares, EC Douglass… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: To determine surgical resectability, event-free survival (EFS), and toxicity in
children with hepatocellular carcinoma (HCC) randomized to treatment with either cisplatin (…