Parkinson’s disease (PD) is a slowly progressive neurodegenerative disorder mainly
characterized by degeneration of dopaminergic neurons in the substantia nigra and the ventral …

Parkinsonism is a clinical syndrome characterized by bradykinesia, hypo-/akinesia, muscular
rigidity, and resting tremor, mainly caused by Parkinson’s disease (PD). Progressive loss of …

Clinical symptoms in Parkinson's disease (PD) comprise both motor and non-motor symptoms.
In this disease, synucleinopathic-induced, nigral dopamine deficiency-related dysfunction …

Magnetic resonance imaging (MRI) has shown a great reduction in medial temporal lobe
and hippocampal volume of patients with Alzheimer's disease as compared to controls. …

Olfactory dysfunction is an early and common symptom in Parkinson's disease (PD). In an
effort to determine whether otherwise unexplained (idiopathic) olfactory dysfunction is …

We have identified a large Dutch kindred with a new form of X-linked nondysmorphic mild
mental retardation. All affected males in this family show very characteristic abnormal behavior…

OBJECTIVES: The main neuropathological feature in Parkinson's disease is a severe
degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine (…

Ellis T, de Goede CJ, Feldman RG, Wolters EC, Kwakkel G, Wagenaar RC. Efficacy of a
physical therapy program in patients with Parkinson’s disease: a randomized controlled trial. …

Article abstract—We investigated the histopathologic correlates of white matter changes in
Alzheimer's disease (AD) patients (n = 6) and controls (n = 9) using postmortem MRT. White …

By the time a clinical diagnosis of Parkinson's disease (PD) is made, a significant loss of
dopaminergic neurons has already occurred. Identifying patients in the period between the …