Early diagnosis of neurodegenerative disorders such as Alzheimer’s (AD) or Parkinson’s
disease (PD) is needed to slow down or halt the disease at the earliest stage. Cerebrospinal …

Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

… E) Normal white matter arterioles in which the deeper pink cells are smooth muscle cells. F)
Severely fibrotic and stenosed arteriole from a case of SSVD (E and F… E) Normal white matter …

The discovery of α-synuclein (α-syn) as a major component of Lewy bodies, neuropathological
hallmark of Parkinson's disease (PD), dementia with Lewy bodies and of glial inclusions …

… Panels B, C, E, and F have secondary y-axes owing to large differences between samples.
… Data points missing in panels B and E are because of experimental error related to high …

Background The cerebrospinal fluid (CSF) biomarkers amyloid beta 1–42, total tau, and
phosphorylated tau are used increasingly for Alzheimer's disease (AD) research and patient …

Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral
amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and …

The purpose of this study was to explore the effects of age and education on the performance
of the Trail Making Test (TMT), and to provide normative data in the Greek population. The …

Importance Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD).
Understanding the association between amyloid aggregation and cognitive manifestation in …

The aim was to quantify tau protein and β-amyloid (Aβ42) in the CSF of patients with
sporadic Creutzfeldt-Jakob disease (CJD), Alzheimer's disease (AD), and controls. Double …