Objective Summarize evidence for use of advanced MRI techniques as monitoring biomarkers
in the clinic, and highlight the latest bench-to-bedside developments. Methods Experts in …

Hypoglycemia is the most frequent complication of insulin therapy in patients with type 1
diabetes. Since the brain is reliant on circulating glucose as its main source of energy, …

Objective: To summarize evidence for use of advanced MRI techniques as monitoring biomarkers
in the clinic, and to highlight the latest bench-to-bedside developments. Methods: The …

Brain lactate may be involved in the development of impaired awareness of hypoglycemia (IAH),
a condition that affects approximately 25% of patients with type 1 diabetes and …

High-intensity interval training (HIIT) has gained increasing popularity in patients with
diabetes. HIIT acutely increases plasma lactate levels. This may be important, since the …

It is unclear whether cerebral blood flow responses to hypoglycemia are altered in people
with type 1 diabetes and impaired awareness of hypoglycemia. The aim of this study was to …

The onco-metabolite 2-hydroxyglutarate (2HG), a biomarker of IDH-mutant gliomas, can be
detected with 1 H MR spectroscopy ( 1 H-MRS). Recent studies showed measurements of …

BACKGROUND AND PURPOSE: Cerebral MR imaging in infants is usually performed with
a field strength of up to 3T. In adults, a growing number of studies have shown added …

Purpose Current challenges of in vivo CEST imaging include overlapping signals from different
pools. The overlap arises from closely resonating pools and/or the broad magnetization …

Aims/hypothesis Chronic hyperglycaemia in type 1 diabetes affects the structure and
functioning of the brain, but the impact of recurrent hypoglycaemia is unclear. Changes in the …