PLGA-based nanoparticles in cancer treatment

…, MK Moraveji, N Güvener, EK Koons… - Frontiers in …, 2018 - frontiersin.org
Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug
delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid) (PLGA)-…

Coronary artery stenosis quantification in patients with dense calcifications using ultra-high-resolution photon-counting-detector computed tomography

EK Koons, PS Rajiah, JE Thorne, NM Weber… - Journal of …, 2024 - Elsevier
Koons et al. demonstrated reduced percent area stenosis with a clinical PCD-CT compared
to conventional EID-CT which overestimated the percent stenosis, more closely matching a …

Pie‐Net: Prior‐information‐enabled deep learning noise reduction for coronary CT angiography acquired with a photon counting detector CT

S Chang, NR Huber, JF Marsh, EK Koons… - Medical …, 2023 - Wiley Online Library
Background Photon‐counting‐detector CT (PCD‐CT) enables the production of virtual
monoenergetic images (VMIs) at a high spatial resolution (HR) via simultaneous acquisition of …

Quantifying lumen diameter in coronary artery stents with high‐resolution photon counting detector CT and convolutional neural network denoising

EK Koons, JE Thorne, NR Huber, S Chang… - Medical …, 2023 - Wiley Online Library
Quantifying lumen diameter in coronary artery stents with high‐resolution photon counting
detector CT and convolutional neural network denoising - Koons - 2023 - Medical Physics - …

PKAID-Net: Prior knowledge aware iterative denoising neural network for photon counting detector CT

S Chang, JF Marsh Jr, EK Koons… - … 2023: Physics of …, 2023 - spiedigitallibrary.org
An important feature enabled by Photon-Counting Detector (PCD) CT is the simultaneous
acquisition of multi-energy data, which can produce virtual monoenergetic images (VMIs) at a …

Minimizing magnetic resonance image geometric distortion at 7 Tesla for frameless presurgical planning using skin‐adhered fiducials

KM Kirby, EK Koons, KM Welker, AJ Fagan - Medical physics, 2023 - Wiley Online Library
Background 7T MRI offers significant benefits to spatial and contrast resolution compared to
lower field strengths. This superior image quality can help better delineate targets in …

Motion artifact correction in cardiac CT using cross-phase temporospatial information and synergistic attention gate and spatial transformer sub-networks

H Gong, Z Ahmed, S Chang, EK Koons… - Physics in Medicine …, 2024 - iopscience.iop.org
Objectives. To improve quality of coronary CT angiography (CCTA) images using a
generalizable motion-correction algorithm. Approach. A neural network with attention gate and …

Learned high-resolution cardiac CT imaging from ultra-high-resolution PCD-CT

EK Koons, H Gong, A Missert, S Chang… - … 2024: Physics of …, 2024 - spiedigitallibrary.org
Coronary computed tomography angiography (cCTA) is a widely used non-invasive
diagnostic exam for patients with coronary artery disease (CAD). However, most clinical CT …

Improving stenosis assessment in energy integrating detector CT via learned monoenergetic imaging capability

S Chang, EK Koons, H Gong, JE Thorne… - … 2024: Physics of …, 2024 - spiedigitallibrary.org
Coronary CT angiography (cCTA) is a fast non-invasive imaging exam for coronary artery
disease (CAD) but struggles with dense calcifications and stents due to blooming artifacts, …

Minimizing MR image geometric distortion at 7 Tesla for frameless presurgical planning using skin-adhered fiducials.

KM Kirby, EK Koons, KM Welker, AJ Fagan - Medical Physics, 2022 - europepmc.org
Background 7T MRI offers significant benefits to spatial and contrast resolution compared to
lower field strengths. This superior image quality can help better delineate targets in …