Clinical trials in traumatic brain injury. What can we learn from previous studies?

EM Doppenberg, SC Choi, R Bullock - … of the New York Academy of …, 1997 - europepmc.org
Many compounds have now been tested that were expected to ameliorate the secondary
ischemic brain damage after severe head injury. Thus far, none of these have been clearly …

Preoperative Onyx embolization of aggressive vertebral hemangiomas

…, CM Mitchell, EM Doppenberg… - American journal …, 2008 - Am Soc Neuroradiology
We report the first use of Onyx in the embolization of spinal tumors in 2 cases of aggressive
vertebral hemangioma. In both cases, Onyx embolization provided effective preoperative …

Glioblastoma multiforme causing calvarial destruction: an unusual manifestation revisited

V Gheyi, FK Hui, EM Doppenberg… - American journal …, 2004 - Am Soc Neuroradiology
This report describes invasion of overlying calvaria and soft tissues by a high-grade glioma
without macroscopic evidence of dural involvement. The initial radiologic examinations …

The rationale for, and effects of oxygen delivery enhancement to ischemic brain in a feline model of human stroke.

EM Doppenberg, JC Watson, R Bullock… - Annals of the New …, 1997 - europepmc.org
Reduced brain tissue oxygenation is frequently seen in severe head injury and after subarachnoid
hemorrhage, and this is considered a major cause of secondary ischemic brain injury. …

Cervical spine instability from tumoral calcinosis

RH Wong, AP Bhansali, EM Doppenberg - Acta neurochirurgica, 2013 - Springer
Dear Editor, In the present case, we describe the clinical presentation, surgical management,
and long-term follow-up of a rare case of tumoral calcinosis-induced cervical spine …

Cerebral oxygen reactivity determination--a simple test with potential prognostic relevance

M Menzel, EM Doppenberg, A Zauner… - Zentralblatt fur …, 2000 - europepmc.org
Brain tissue oximetry (ptiO2) using flexible micro-polarographic electrodes is a loco-regional
approach to monitor oxygen supply to the injured brain, after neuronal damage. In patients …

[PDF][PDF] Closed Stereotactic Needle Biopsy of Brainstem Small Cell Glioblastoma: A Case Report and Literature Review

S Jadidi, A D'Abarno, EM Doppenberg - Cureus, 2018 - cureus.com
Glioblastoma is the deadliest and most common of the malignant primary brain tumors that
can occur in adults. In contrast, brainstem gliomas are extremely uncommon in adults; …

An open‐label study of CP‐101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral hemorrhage

…, CA Carmack, E Doppenberg… - Annals of the New …, 1999 - Wiley Online Library
… for both EM and PM patients. The plasma CP-101,606 concentrations in the 17 EM patients
who … Three EM patients' CSF concentrations of drug were examined. CP-101,606 entered the …

FOLFIRINOX as initial treatment for localized pancreatic adenocarcinoma: a retrospective analysis by the Trans-Atlantic Pancreatic Surgery Consortium

…, JL Van Dam, D Doppenberg… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Large pragmatic studies of patients who received 5-fluorouracil with leucovorin,
irinotecan, and oxaliplatin ([m]FOLFIRINOX) as initial treatment for localized pancreatic …

Neoadjuvant radiotherapy after (m) FOLFIRINOX for borderline resectable pancreatic adenocarcinoma: A TAPS Consortium study

…, JL van Dam, LR Prakash, D Doppenberg… - Journal of the National …, 2022 - jnccn.org
Background: The value of neoadjuvant radiotherapy (RT) after 5-fluorouracil with leucovorin,
oxaliplatin, and irinotecan, with or without dose modifications [(m) FOLFIRINOX], for …