Classification of brain tumor type and grade using MRI texture and shape in a machine learning scheme

…, D Soo Yoo, R Wolf, ER Melhem… - … in Medicine: An …, 2009 - Wiley Online Library
The objective of this study is to investigate the use of pattern classification methods for
distinguishing different types of brain tumors, such as primary gliomas from metastases, and also …

Imaging cortical association tracts in the human brain using diffusion‐tensor‐based axonal tracking

…, GD Pearlson, ER Melhem… - … in Medicine: An …, 2002 - Wiley Online Library
Diffusion‐tensor fiber tracking was used to identify the cores of several long‐association
fibers, including the anterior (ATR) and posterior (PTR) thalamic radiations, and the uncinate (…

Diffusion tensor MR imaging of the brain and white matter tractography

ER Melhem, S Mori, G Mukundan… - American Journal of …, 2002 - Am Roentgen Ray Soc
Background Random motion of water molecules (diffusion) in the presence of a strong magnetic
gradient results in MR signal loss as a result of the dephasing of spin coherence (Fig. 1)…

Diffusion-Tensor MR Imaging and Tractography: Exploring Brain Microstructure and Connectivity1

PGP Nucifora, R Verma, SK Lee, ER Melhem - Radiology, 2007 - pubs.rsna.org
Diffusion magnetic resonance (MR) imaging is evolving into a potent tool in the examination
of the central nervous system. Although it is often used for the detection of acute ischemia, …

Diffusion kurtosis imaging: an emerging technique for evaluating the microstructural environment of the brain

AJ Steven, J Zhuo, ER Melhem - American journal of …, 2014 - Am Roentgen Ray Soc
OBJECTIVE. Diffusion kurtosis imaging is an emerging technique based on the non-gaussian
diffusion of water in biologic systems. The purpose of this article is to introduce and …

Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults

RN Al-Okaili, J Krejza, S Wang, JH Woo, ER Melhem - Radiographics, 2006 - pubs.rsna.org
Intraaxial brain masses are a significant health problem and present several imaging
challenges. The role of imaging is no longer limited to merely providing anatomic details. …

Computer-assisted segmentation of white matter lesions in 3D MR images using support vector machine

Z Lao, D Shen, D Liu, AF Jawad, ER Melhem… - Academic radiology, 2008 - Elsevier
RATIONALE AND OBJECTIVES: Brain lesions, especially white matter lesions (WMLs), are
associated with cardiac and vascular disease, but also with normal aging. Quantitative …

GLISTR: glioma image segmentation and registration

…, M Bilello, L Cirillo, G Biros, ER Melhem… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
We present a generative approach for simultaneously registering a probabilistic atlas of a
healthy population to brain magnetic resonance (MR) scans showing glioma and segmenting …

High-dimensional spatial normalization of diffusion tensor images improves the detection of white matter differences: an example study using amyotrophic lateral …

…, LF McCluskey, LB Elman, ER Melhem… - IEEE transactions on …, 2007 - ieeexplore.ieee.org
Spatial normalization of diffusion tensor images plays a key role in voxel-based analysis of
white matter (WM) group differences. Currently, it has been achieved using low-dimensional …

Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil

…, J Xu, RO Jones, DJ Loes, ER Melhem… - Archives of …, 2005 - jamanetwork.com
Objectives To identify asymptomatic boys with X-linked adrenoleukodystrophy who have a
normal magnetic resonance image (MRI), and to assess the effect of 4:1 glyceryl trioleate–…