Brain MRI atrophy quantification in MS: from methods to clinical application
Patients with the main clinical phenotypes of multiple sclerosis (MS) manifest varying degrees
of brain atrophy beyond that of normal aging. Assessment of atrophy helps to distinguish …
of brain atrophy beyond that of normal aging. Assessment of atrophy helps to distinguish …
Diffusion tensor MR imaging
Diffusion tensor (DT) MR imaging is able to detect and quantify multiple sclerosis (MS)–related
tissue damage within and outside T2-visible lesions. DT MR imaging has also been …
tissue damage within and outside T2-visible lesions. DT MR imaging has also been …
Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis
M Cercignani, M Inglese, E Pagani… - American journal of …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Compared with conventional T2-weighted MR imaging,
diffusion tensor MR imaging provides quantitative indices with increased specificity to the most …
diffusion tensor MR imaging provides quantitative indices with increased specificity to the most …
Basic concepts of advanced MRI techniques
An overview is given of magnetic resonance (MR) techniques sensitized to diffusion, flow,
magnetization transfer effect, and local field inhomogeneities induced by physiological …
magnetization transfer effect, and local field inhomogeneities induced by physiological …
Glymphatic system impairment in multiple sclerosis: relation with brain damage and disability
Recent evidence has shown the existence of a CNS ‘waste clearance’ system, defined as
the glymphatic system. Glymphatic abnormalities have been described in several …
the glymphatic system. Glymphatic abnormalities have been described in several …
A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes
A Ceccarelli, MA Rocca, E Pagani, B Colombo… - Neuroimage, 2008 - Elsevier
To assess regional grey matter (GM) changes in a large cohort of multiple sclerosis (MS)
patients with different clinical phenotypes, using voxel-based morphometry (VBM) and their …
patients with different clinical phenotypes, using voxel-based morphometry (VBM) and their …
Multiple sclerosis: effects of cognitive rehabilitation on structural and functional MR imaging measures—an explorative study
…, F Mattioli, R Capra, C Stampatori, E Pagani… - Radiology, 2012 - pubs.rsna.org
Purpose To evaluate brain changes after cognitive rehabilitation in patients with clinically
stable relapsing-remitting (RR) multiple sclerosis (MS) by using neuropsychologic assessment …
stable relapsing-remitting (RR) multiple sclerosis (MS) by using neuropsychologic assessment …
Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype
E Pagani, MA Rocca, A Gallo… - American Journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Progressive brain atrophy is a well-known feature of
multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS …
multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS …
Thalamic damage and long-term progression of disability in multiple sclerosis
MA Rocca, S Mesaros, E Pagani, MP Sormani, G Comi… - Radiology, 2010 - pubs.rsna.org
Purpose To estimate the relative contributions of baseline thalamic atrophy and abnormalities
shown at magnetization transfer (MT) magnetic resonance (MR) imaging, as well as their …
shown at magnetization transfer (MT) magnetic resonance (MR) imaging, as well as their …
A method for obtaining tract-specific diffusion tensor MRI measurements in the presence of disease: application to patients with clinically isolated syndromes …
The aim of this study was to investigate whether neurological symptoms related to a specific
axonal fiber tract in brain white matter were associated with a higher degree of tissue …
axonal fiber tract in brain white matter were associated with a higher degree of tissue …