OBJECT Chiari malformation Type I (CM-I) is a hindbrain disorder associated with elongation
of the cerebellar tonsils, which descend below the foramen magnum into the spinal canal. …

Medulloblastoma encompasses a collection of clinically and molecularly diverse tumour
subtypes that together comprise the most common malignant childhood brain tumour 1 , 2 , 3 , 4 …

Background Therapy for ependymoma includes aggressive surgical intervention and
radiotherapy administered by use of methods that keep the risk of side-effects to a minimum. We …

OBJECTIVE Worldwide disparities in the provision of surgical care result in otherwise
preventable disability and death. There is a growing need to quantify the global burden of …

Understanding the biology that underlies histologically similar but molecularly distinct
subgroups of cancer has proven difficult because their defining genetic alterations are often …

Low-grade neuroepithelial tumors (LGNTs) are diverse CNS tumors presenting in children
and young adults, often with a history of epilepsy. While the genetic profiles of common LGNTs…

Object Neurosurgeons are inundated with vast amounts of new clinical research on a daily
basis, making it difficult and time-consuming to keep up with the latest literature. Meta-…

Purpose We conducted a phase II trial of conformal radiation therapy (CRT) for localized
childhood ependymoma to determine whether the irradiated volume could be reduced to …

OBJECTIVE Outpatient anterior cervical discectomy and fusion (ACDF) is becoming more
common and has been reported to offer advantages over inpatient procedures, including …

Object. Endoscopically assisted ventricular catheter placement has been reported to reduce
shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in …