User profiles for F Gonzalez-Scarano

Francisco Gonzalez-Scarano

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 15598

Microglia as mediators of inflammatory and degenerative diseases

F González-Scarano, G Baltuch - Annual review of neuroscience, 1999 - annualreviews.org
▪ Abstract Microglia are the principal immune cells in the central nervous system (CNS) and
have a critical role in host defense against invading microorganisms and neoplastic cells. …

The neuropathogenesis of AIDS

F González-Scarano, J Martín-García - Nature reviews immunology, 2005 - nature.com
HIV-associated dementia (HAD) is an important complication of the central nervous system
in patients who are infected with HIV-1. Although the incidence of HAD has markedly …

Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging.

…, MD Schnall, LH Young, F Gonzalez-Scarano… - Radiology, 1992 - pubs.rsna.org
Magnetization transfer imaging (MTI) was initially performed in normal guinea pigs and
human volunteers. A magnetization transfer ratio (MTR) was calculated in the normal white …

HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment

S Spudich, F González-Scarano - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
HIV-associated central nervous system (CNS) injury continues to be clinically significant in
the modern era of HIV infection and therapy. A substantial proportion of patients with …

Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide

…, K Stefano, DH Silberberg, F Gonzalez-Scarano - Science, 1991 - science.org
Although the CD4 molecule is the principal cellular receptor for the human immunodeficiency
virus (HIV), several CD4-negative cell lines are susceptible to infection with one or more …

Arboviral encephalitides: transmission, emergence, and pathogenesis

BS Hollidge, F González-Scarano… - Journal of neuroimmune …, 2010 - Springer
… that LACV V22 had decreased replication in peripheral tissues (eg, striated muscle) critical
for the generation of a high viremia following peripheral inoculation (Gonzalez-Scarano et al. …

Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates

…, MJ O'Connor, RW Doms, F González-Scarano - Journal of …, 1999 - Am Soc Microbiol
Microglia are the main human immunodeficiency virus (HIV) reservoir in the central nervous
system and most likely play a major role in the development of HIV dementia (HIVD). To …

Severe fever with thrombocytopenia virus glycoproteins are targeted by neutralizing antibodies and can use DC-SIGN as a receptor for pH-dependent entry into …

…, F Kaup, SS Soldan, F González-Scarano… - Journal of …, 2013 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel bunyavirus that
recently emerged in China. Infection with SFTSV is associated with case-fatality rates of up to 30…

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and …

…, JA Hoxie, F González-Scarano - The American journal …, 1997 - ncbi.nlm.nih.gov
… Strizki JM, Albright AV, Sheng H, O'Connor M, Perrin L, GonzalezScarano F: Infection of …
Albright AV, Strizki J, Harouse JM, Lavi E, O'Connor M, GonzalezScarano F: HIV-1 infection …

Multiple sclerosis: gadolinium enhancement in MR imaging.

RI Grossman, F Gonzalez-Scarano, SW Atlas, S Galetta… - Radiology, 1986 - pubs.rsna.org
Magnetic resonance (MR) images--both nonenhanced and enhanced with gadolinium
DTPA/dimeglumine (Gd)--were compared with high-iodine (88.1 g I) computed tomographic (HICT…