Background— The purpose of this statement is to provide an overview of cerebral venous
sinus thrombosis and to provide recommendations for its diagnosis, management, and …

Survivin is a member of the inhibitor-of-apoptosis proteins (IAPs) family; its overexpression
has been widely demonstrated to occur in various types of cancer. Overexpression of survivin …

Since the discovery of survivin (BIRC5) as a cancer-related molecule by Grazia Ambrosini
and Dario C. Altieri at 1997, our knowledge related to the function of this molecule has been …

Blood cell development relies on the expansion and maintenance of haematopoietic stem
and progenitor cells in the embryo. By gene targeting in mouse embryonic stem cells, we …

Members of the E2F transcription factor family (E2F-1–E2F-5) are believed to be critical
positive regulators of cell cycle progression in eukaryotes although the in vivo functions of the …

In this study a series of steady flow in vitro experiments are described in which important
hydrodynamic factors, including pressure drop, separation, and turbulence, are considered for …

The zinc-finger transcription factor GATA-2 plays a critical role in maintaining the pool of
early hematopoietic cells. To define its specific functions in the proliferation, survival, and …

Tumors develop through successive stages characterized by changes in gene expression
and protein function. Gene expression profiling of pancreatic islet tumors in a mouse model of …

In Part I of this paper the effect of a stenosis on the steady flow through a tube was
considered. In Part II the effect of unsteadiness is investigated experimentally using the same …

GATA-2 is an essential transcription factor in the hematopoietic system that is expressed in
hematopoietic stem cells (HSCs) and progenitors. Complete deficiency of GATA-2 in the …