A frequent problem in analysis is the need to find two matrices, closely related to the
underlying measurement process, which when multiplied together reproduce the matrix of data …

Context: GH and IGF-I are nitrogen retaining and anabolic, but the impact of long-term
exposure to supraphysiological GH and IGF-I, either from endogenous overproduction in …

Context: GH and IGF-I have important roles in the maintenance of substrate metabolism and
body composition. However, when in excess in acromegaly, the lipolytic and insulin …

Intracerebral convection-enhanced delivery (CED) of chemotherapeutic agents currently
requires an externalized catheter and infusion system, which limits its duration because of the …

A multi‐institutional group has been created to demonstrate the utility of in vivo 31 P magnetic
resonance spectroscopy ( 31 P‐MRS) to study human cancers in vivo. This review is …

The standardization and reproducibility of techniques required to acquire anatomically
localized 31 P MR spectra non‐invasively while studying tumors in cancer patients in a multi‐…

… F. Arias-Mendoza and TR Brown / In vivo measurement of phosphorous markers of disease
… Arias-Mendoza and TR Brown / In vivo measurement of phosphorous markers of disease …

RATIONALE AND OBJECTIVES: Phosphoethanolamine and phosphocholine, shown to be
elevated in tumors and possibly related to apoptotic signaling, have the potential to be …

Balanced pools of deoxyribonucleoside triphosphate precursors are required for DNA replication,
and alterations of this balance are relevant to human mitochondrial diseases including …

We report acquisition of 3D image‐guided localized proton spectroscopy ( 1 H‐MRS) in the
human brain on a standard clinical imager. 3D coverage is achieved with a hybrid of …