Digital therapeutics in neurology

…, F Brigo, M Clerico, S De Mercanti, F Trojsi… - Journal of …, 2022 - Springer
Digital therapeutics (DTx) is a section of digital health defined by the DTx Alliance as “delivering
evidence-based therapeutic interventions to patients that are driven by software to …

[HTML][HTML] Social cognition dysfunctions in neurodegenerative diseases: neuroanatomical correlates and clinical implications

…, H Santamaría-García, G Santangelo, F Trojsi - Behavioural …, 2018 - hindawi.com
… Correspondence should be addressed to Francesca Trojsi; francesca.trojsi@unicampania.it …
rather than cognitive component of ToM [157], Trojsi et al. [136] found that both cognitive …

[PDF][PDF] Genome-wide analyses identify KIF5A as a novel ALS gene

…, L Tremolizzo, A Arosio, C Ferrarese, F Trojsi… - Neuron, 2018 - cell.com
To identify novel genes associated with ALS, we undertook two lines of investigation. We
carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls…

Exposure to environmental toxicants and pathogenesis of amyotrophic lateral sclerosis: state of the art and research perspectives

F Trojsi, MR Monsurrò, G Tedeschi - International journal of molecular …, 2013 - mdpi.com
There is a broad scientific consensus that amyotrophic lateral sclerosis (ALS), a fatal
neuromuscular disease, is caused by gene-environment interactions. In fact, given that only about …

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis

…, S Tranquilli, L Tremolizzo, F Trojsi… - Annals of …, 2019 - Wiley Online Library
F-statistic parameter as described elsewhere.47 Our results showed that two of the three
GWASes of interest for which the F… samples (F-statistic for LDL cholesterol = 59.02; F-statistic for …

Nusinersen safety and effects on motor function in adult spinal muscular atrophy type 2 and 3

…, L Passamano, M Grandis, F Trojsi, F Cerri… - Journal of Neurology …, 2020 - jnnp.bmj.com
… Data for SMA2 are shown in panels A and D, while data for SMA3 sitters are shown in
panels B and E, and those for SMA3 ‘walkers’ in panels C and F. Boxes identify first to third …

Multidimensional assessment of the effects of erenumab in chronic migraine patients with previous unsuccessful preventive treatments: a comprehensive real-world …

…, M Silvestro, F Scotto di Clemente, F Trojsi… - The journal of headache …, 2020 - Springer
Background erenumab was safe and effective in clinical trials for the prevention of migraine.
However, real-life data are still lacking. Here we report the clinical experience from an …

Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent and malignancy

A Di Costanzo, T Scarabino, F Trojsi, GM Giannatempo… - Neuroradiology, 2006 - Springer
Introduction Contrast-enhanced MR imaging is the method of choice for routine assessment
of brain tumors, but it has limited sensitivity and specificity. We verified if the addition of …

Factors predicting survival in ALS: a multicenter Italian study

…, N Ticozzi, GD Ferrante, C Scialo, G Sorarù, F Trojsi… - Journal of …, 2017 - Springer
f Kaplan–Meier survival estimates according to the presence of dementia (survival from …
Outside this work, Francesca Trojsi perceived Grants from Novartis and Maria Rosaria Monsurrò …

Interaction between aging and neurodegeneration in amyotrophic lateral sclerosis

G Tedeschi, F Trojsi, A Tessitore, D Corbo… - Neurobiology of …, 2012 - Elsevier
We assessed the spontaneous blood-oxygen-level-dependent signal fluctuations in the
resting-state brain networks of amyotrophic lateral sclerosis patients and their relation to …