Role of blood clot formation on early edema development after experimental intracerebral hemorrhage

…, KR Wagner, RF Keep, Y Hua, GM de Courten-Myers… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Blood “toxicity” is hypothesized to induce edema and brain
tissue injury following intracerebral hemorrhage (ICH). Lobar ICH in pigs produces rapidly …

Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matter

…, G Xi, Y Hua, M Kleinholz, GM de Courten-Myers… - Stroke, 1996 - Am Heart Assoc
Background and Purpose The mechanisms underlying brain injury from intracerebral
hemorrhage (ICH) are complex and poorly understood. To comprehensively examine …

Protein oxidation and heme oxygenase-1 induction in porcine white matter following intracerebral infusions of whole blood or plasma

…, MJ Linke, GM de Courten-Myers… - Developmental …, 2002 - karger.com
Spontaneous or traumatic intracerebral hemorrhage (ICH) in the white matter of neonates,
children and adults causes significant mortality and morbidity. The detailed biochemical …

Correlation of cavitation with ultrasound enhancement of thrombolysis

…, J Tan, T Porter, G De Courten-Myers… - Ultrasound in medicine …, 2006 - Elsevier
Pulsed ultrasound, when used as an adjuvant to recombinant tissue plasminogen activator (rt-PA),
has been shown to enhance thrombolysis in the laboratory as well as in clinical trials …

Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier …

…, Y Hua, M Zuccarello, GM de Courten-Myers… - Journal of …, 1999 - thejns.org
Object. Ultra-early hematoma evacuation (< 4 hours) after intracerebral hemorrhage (ICH)
may reduce mass effect and edema development and improve outcome. To test this …

Ultrasound-enhanced thrombolysis using Definity® as a cavitation nucleation agent

…, AY Ammi, TD Mast, GM de Courten-Myers… - Ultrasound in medicine …, 2008 - Elsevier
Ultrasound has been shown previously to act synergistically with a thrombolytic agent, such
as recombinant tissue plasminogen activator (rt-PA) to accelerate thrombolysis. In this in …

The human cerebral cortex: gender differences in structure and function

GM De Courten-Myers - Journal of Neuropathology and …, 1999 - academic.oup.com
… Dean DE, Petctot JM-C, de Courten-Myers GM. Gender differences in the human cerebral
cortex: Morc neurons in males; more processcs in femalcs. J Child Neurol 1998; 13 (in press) …

Human cortex development: estimates of neuronal numbers indicate major loss late during gestation

T Rabinowicz, GM de Courten-Myers… - Journal of …, 1996 - academic.oup.com
This morphometric study explores temporal and topographic changes in the estimated
neuronal number in human neocortex during the latter half of gestation and early infancy. …

Gender differences in the human cerebral cortex: more neurons in males; more processes in females

…, GM de Courten-Myers - Journal of Child …, 1999 - journals.sagepub.com
This study's objective was to investigate morphometric gender differences of the cerebral
cortex in six males and five females, 12 to 24 years old. Though human brains lack sexual …

Early metabolic alterations in edematous perihematomal brain regions following experimental intracerebral hemorrhage

…, G Xi, Y Hua, M Kleinholz, GM de Courten-Myers… - Journal of …, 1998 - thejns.org
… Also, our hematomal lactate levels are only 5 to 8 mol/g (data not shown), values that are
considerably lower than those present in edematous white matter. Increased brain tissue …