User profiles for G. Barisano

Giuseppe Barisano

MD PhD, Stanford University
Verified email at stanford.edu
Cited by 1759

Blood–brain barrier link to human cognitive impairment and Alzheimer's disease

G Barisano, A Montagne, K Kisler… - Nature cardiovascular …, 2022 - nature.com
Vascular dysfunction is frequently observed in disorders associated with cognitive impairment,
dementia and Alzheimer’s disease (AD). Recent advances in neuroimaging and fluid …

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

A Montagne, DA Nation, AP Sagare, G Barisano… - Nature, 2020 - nature.com
… f, g, Baseline CSF sPDGFRβ does not predict decline (n = 88) in either mental status (f) or
global composite (g) scores in APOE3 homozygotes regardless of CSF Aβ or pTau status. b–g, …

[HTML][HTML] Imaging perivascular space structure and function using brain MRI

G Barisano, KM Lynch, F Sibilia, H Lan, NC Shih… - Neuroimage, 2022 - Elsevier
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing number of …

Clinical 7 T MRI: Are we there yet? A review about magnetic resonance imaging at ultra-high field

G Barisano, F Sepehrband, S Ma, K Jann… - The British journal of …, 2019 - academic.oup.com
In recent years, ultra-high field MRI (7 T and above) has received more interest for clinical
imaging. Indeed, a number of studies have shown the benefits from the application of this …

[HTML][HTML] A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms

…, A Zavaliangos-Petropulu, JN Jeong, G Barisano… - Scientific data, 2022 - nature.com
Accurate lesion segmentation is critical in stroke rehabilitation research for the quantification
of lesion burden and accurate image processing. Current automated lesion segmentation …

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice

G Barisano, K Kisler, B Wilkinson… - Journal of Experimental …, 2022 - rupress.org
… 3 G). A lower number of phosphorylation sites were found in proteins involved in trafficking
and GTP signaling molecules, solute transport, protein degradation, and cell adhesion along …

The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts

G Barisano, F Sepehrband… - Proceedings of the …, 2022 - National Acad Sciences
… The spaceflight-associated PVS dilation (E and F) and VSA reduction (G) were not
significantly different between the groups, but a significantly greater LV enlargement (H) was …

Body mass index, time of day and genetics affect perivascular spaces in the white matter

G Barisano, N Sheikh-Bahaei, M Law… - Journal of Cerebral …, 2021 - journals.sagepub.com
The analysis of cerebral perivascular spaces (PVS) using magnetic resonance imaging (MRI)
allows to explore in vivo their contributions to neurological disorders. To date the normal …

[HTML][HTML] Image processing approaches to enhance perivascular space visibility and quantification using MRI

F Sepehrband, G Barisano, N Sheikh-Bahaei… - Scientific reports, 2019 - nature.com
Imaging the perivascular spaces (PVS), also known as Virchow-Robin space, has significant
clinical value, but there remains a need for neuroimaging techniques to improve mapping …

Volumetric distribution of perivascular space in relation to mild cognitive impairment

F Sepehrband, G Barisano, N Sheikh-Bahaei… - Neurobiology of …, 2021 - Elsevier
Vascular contributions to early cognitive decline are increasingly recognized, prompting
further investigation into the nature of related changes in perivascular spaces (PVS). Using …