Alzheimer’s disease (AD) is the most common type of dementia in the elderly population.
Three genes have been identified as responsible for the rare early-onset familial form of the …

Complex and inter-related factors explain the excessive use of fertilizer observed in many
intensive farming systems in China, and hence act as barriers to development of a …

Astrocytes have long been considered as just providing trophic support for neurons in the
central nervous system, but recently several studies have highlighted their importance in many …

We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Apolipoprotein E (APOE) dependent lifetime risks (LTRs) for Alzheimer Disease (AD) are
currently not accurately known and odds ratios alone are insufficient to assess these risks. We …

… PFN1 is crucial for the conversion of monomeric (G)-actin to filamentous (F)-actin. Exome …
smaller growth cones with a reduced F/G-actin ratio. These observations further document …

… b) or lithium (c and d) and from G93A mice treated with saline (e and g) or lithium (f and h).
(g) In G93A mice treated with saline, TEM shows mitochondrial vacuolization (arrowheads). (f …

Background In patients with Multiple Sclerosis (pwMS) disease-modifying therapies (DMTs)
affects immune response to antigens. Therefore, post-vaccination serological assessments …

… at 500 × g at 4C for 5 min. The pellet was washed with the homogenization buffer and
centrifuged at 500 × g for 5 min (4C). The supernatant was centrifuged at 10,000 × g at 4C for 15 …

It is well established that oxidative stress plays a key role in the degenerative neuronal
death and progression of Alzheimer's disease (AD), although it is not clear if it is the primary …