User profiles for G. Zanazzi

George Zanazzi

Dartmouth-Hitchcock Medical Center
Verified email at dartmouth.edu
Cited by 4338

[HTML][HTML] Neuregulin-1 type III determines the ensheathment fate of axons

C Taveggia, G Zanazzi, A Petrylak, H Yano… - Neuron, 2005 - cell.com
The signals that determine whether axons are ensheathed or myelinated by Schwann cells
have long been elusive. We now report that threshold levels of neuregulin-1 (NRG1) type III …

The molecular architecture of ribbon presynaptic terminals

G Zanazzi, G Matthews - Molecular neurobiology, 2009 - Springer
The primary receptor neurons of the auditory, vestibular, and visual systems encode a
broad range of sensory information by modulating the tonic release of the neurotransmitter …

The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination

S Einheber, G Zanazzi, W Ching, S Scherer… - The Journal of cell …, 1997 - rupress.org
… that ankyrin G, a marker of the nodal cytoskeleton (Kordeli and Bennett, 1991), accumulates
at the node several days before the accumulation of Caspr in the paranodes (Zanazzi, G., V. …

Role of α-Dystroglycan as a Schwann Cell Receptor for Mycobacterium leprae

A Rambukkana, H Yamada, G Zanazzi, T Mathus… - Science, 1998 - science.org
… Mycobacterium lepraespecifically bound to α-DG only in the presence of the G domain of
the α2 chain of laminin-2. Native α-DG competitively inhibited the laminin-2–mediated M. …

[HTML][HTML] Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae

V Ng, G Zanazzi, R Timpl, JF Talts, JL Salzer… - Cell, 2000 - cell.com
The cell wall of pathogenic mycobacteria is abundant with complex glycolipids whose roles
in disease pathogenesis are mostly unknown. Here, we provide evidence for the …

Contact-Dependent Demyelination by Mycobacterium leprae in the Absence of Immune Cells

A Rambukkana, G Zanazzi, N Tapinos, JL Salzer - Science, 2002 - science.org
… (G) Quantification of in vivo demyelination revealed a significant difference (P < 0.0005) in
the number of demyelinated fibers in the sciatic nerves infected with viable M. leprae (ML) and …

[HTML][HTML] Single-cell transcriptome analysis of lineage diversity in high-grade glioma

…, J Samanamud, M Ceccarelli, A Dovas, G Zanazzi… - Genome medicine, 2018 - Springer
… Degenerate CBs containing either ‘N’s or more than four consecutive ‘G’s were discarded.
Synthesis errors, which can result in truncated 11-nt barcodes, were corrected similarly to a …

Aggressive resection at the infiltrative margins of glioblastoma facilitated by intraoperative fluorescein guidance

…, DS Chow, JL Samanamud, GJ Zanazzi… - Journal of …, 2016 - thejns.org
OBJECTIVE Extent of resection is an important prognostic factor in patients undergoing
surgery for glioblastoma (GBM). Recent evidence suggests that intravenously administered …

Expression of caveolin-1 and-2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury

F Galbiati, D Volonté, O Gil, G Zanazzi… - Proceedings of the …, 1998 - National Acad Sciences
… In contrast, in low mitogen medium supplemented with NGF, these cells enter G 0 and
extend long neurites and acquire many of the characteristics of sympathetic neurons. Fig. 1A …

Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination

G Zanazzi, S Einheber, R Westreich… - The Journal of cell …, 2001 - rupress.org
… (Zanazzi, G., and J. Salzer, unpublished observations). These results also suggest that, as
myelin debris is cleared and possibly erbB expression is upregulated, GGF is able to drive …