Importance Continuous morphine infusion as standard postoperative analgesic therapy in
young infants is associated with unwanted adverse effects such as respiratory depression. …

… With regard to brain morphology, van den Bosch et al87 found strong, negative correlations
between neonatal opioid exposure and volumes of pain-related brain regions, total gray …

Pain in newborn children should be prevented due to negative short- and long-term
consequences. A good understanding of the development of the nociceptive system in newborns is …

Beta-blockers are often used during pregnancy to treat cardiovascular diseases. The described
neonatal side effects of maternal beta-blocker use are hypoglycemia and bradycardia, …

… For more details, see van den Bosch et al. [20]. … 23 van den Bosch GE, White T, Tibboel D,
van Dijk M: Functional MRI pain studies in children? Yes, we (s)can! Pediatr Radiol 2013; 43: …

… Gerbrich van den Bosch conceptualized and designed the study, included patients,
supervised initial analyses, critically reviewed and revised the manuscript, and approved the final …

Working memory (WkM) is a fundamental cognitive process that serves as a building block
for higher order cognitive functions. While studies have shown that children and adolescents …

… 13.van den Bosch GE, Van Hemmen J, White T, Tibboel D, Peters JW, van der Geest JN.
Standard and individually determined thermal pain stimuli induce similar brain activations. Eur …

INTRODUCTION: Severe acute asthma in children is associated with substantial morbidity
and may require pediatric ICU (PICU) admission. The aim of the study was to determine risk …

… MRI data were acquired on a 3 Tesla GE MR-750 system using an eight-channel head coil
(General Electric, Milwaukee, WI). A full description of these methods is provided in Appendix …