User profiles for G.V. Goldmacher
 | Gregory V Goldmacher, MD, PhD, MBAMerck Research Laboratories Verified email at merck.com Cited by 2720 |
[HTML][HTML] Response criteria for intratumoral immunotherapy in solid tumors: itRECIST
GV Goldmacher, AD Khilnani… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
Intratumoral (IT) immunotherapy is approved for stage IIIB to IV melanoma 1-5 and under
evaluation in other malignancies with novel immune-stimulatory products. 6-18 Standardized …
evaluation in other malignancies with novel immune-stimulatory products. 6-18 Standardized …
CT cerebral blood flow maps optimally correlate with admission diffusion-weighted imaging in acute stroke but thresholds vary by postprocessing platform
Background and Purpose— Admission infarct core lesion size is an important determinant of
management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine …
management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine …
The use of tumour volumetrics to assess response to therapy in anticancer clinical trials
GV Goldmacher, J Conklin - British journal of clinical …, 2012 - Wiley Online Library
Serial evaluations of tumour burden using imaging, mainly computed tomography and
magnetic resonance imaging, form the basis for assessing treatment response in many clinical …
magnetic resonance imaging, form the basis for assessing treatment response in many clinical …
Early readout on overall survival of patients with melanoma treated with immunotherapy using a novel imaging analysis
…, S Karovic, ML Maitland, GV Goldmacher… - JAMA …, 2022 - jamanetwork.com
… Dr Goldmacher reported stock and other ownership interests in Merck & Co Inc, and Beta
Bionics. Dr Oxnard reported receiving honoraria from Chugai Pharmaceutical Co, Ltd, Bio-Rad …
Bionics. Dr Oxnard reported receiving honoraria from Chugai Pharmaceutical Co, Ltd, Bio-Rad …
[HTML][HTML] Good outcome rate of 35% in IV-tPA–treated patients with computed tomography angiography confirmed severe anterior circulation occlusive stroke
Prospectively, 649 patients with acute stroke had admission National Institutes of Health
stroke scale (NIHSS) scores, noncontrast computed tomography (CT), CT angiography (CTA), …
stroke scale (NIHSS) scores, noncontrast computed tomography (CT), CT angiography (CTA), …
[HTML][HTML] Improved outcome prediction using CT angiography in addition to standard ischemic stroke assessment: results from the STOPStroke study
Purpose To improve ischemic stroke outcome prediction using imaging information from a
prospective cohort who received admission CT angiography (CTA). Methods In a …
prospective cohort who received admission CT angiography (CTA). Methods In a …
[HTML][HTML] Tracking transplanted bone marrow stem cells and their effects in the rat MCAO stroke model
GV Goldmacher, R Nasser, DY Lee, S Yigit… - PloS one, 2013 - journals.plos.org
In this study, rat bone marrow stromal stem cells (BMSCs) were tracked after IV administration
to rats with experimental stroke caused by middle cerebral artery occlusion (MCAO). In …
to rats with experimental stroke caused by middle cerebral artery occlusion (MCAO). In …
[HTML][HTML] Deep learning for classification of pediatric chest radiographs by WHO's standardized methodology
…, CS Roberts, W Ou, T Petigara, GV Goldmacher… - PLoS one, 2021 - journals.plos.org
Background The World Health Organization (WHO)-defined radiological pneumonia is a
preferred endpoint in pneumococcal vaccine efficacy and effectiveness studies in children. …
preferred endpoint in pneumococcal vaccine efficacy and effectiveness studies in children. …
Comparing RECIST 1.1 and iRECIST in advanced melanoma patients treated with pembrolizumab in a phase II clinical trial
FS Ahmed, L Dercle, GV Goldmacher, H Yang… - European …, 2021 - Springer
Objectives To compare tumor best overall response (BOR) by RECIST 1.1 and iRECIST, to
explore the incidence of pseudoprogression in melanoma treated with pembrolizumab, and …
explore the incidence of pseudoprogression in melanoma treated with pembrolizumab, and …
[HTML][HTML] Standardized brain tumor imaging protocol for clinical trials
GV Goldmacher, BM Ellingson… - … : American Journal of …, 2015 - ncbi.nlm.nih.gov
Imaging is critical in the assessment of treatment response in glioblastoma, but its use faces
a variety of challenges, including the morphologic complexity of these tumors, the …
a variety of challenges, including the morphologic complexity of these tumors, the …