Common genetic determinants of vitamin D insufficiency: a genome-wide association study

…, B Kato, DJ Smyth, SL Booth, PF Jacques, GL Burke… - The Lancet, 2010 - thelancet.com
Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

…, ME Kleber, J Huang, AD Johnson, M Li, GL Burke… - Nature, 2015 - nature.com
Myocardial infarction (MI), a leading cause of death around the world, displays a complex
pattern of inheritance 1 , 2 . When MI occurs early in life, genetic inheritance is a major …

Mortality and cardiac and vascular outcomes in extremely obese women

K McTigue, JC Larson, A Valoski, G Burke, J Kotchen… - Jama, 2006 - jamanetwork.com
ContextObesity, typically measured as body mass index of 30 or higher, has 3 subclasses:
obesity 1 (30-34.9); obesity 2 (35-39.9); and extreme obesity (≥40). Extreme obesity is …

Frailty in older adults: evidence for a phenotype

…, T Seeman, R Tracy, WJ Kop, G Burke… - The Journals of …, 2001 - academic.oup.com
Background. Frailty is considered highly prevalent in old age and to confer high risk for falls,
disability, hospitalization, and mortality. Frailty has been considered synonymous with …

Nuclear magnetic resonance spectroscopy of lipoproteins and risk of coronary heart disease in the cardiovascular health study

…, A Arnold, R Tracy, J Otvos, G Burke… - … , and vascular biology, 2002 - Am Heart Assoc
Objectives— Relationships between incident cardiovascular disease and lipoprotein
subclass measurements by nuclear magnetic resonance spectroscopy were evaluated in the …

[HTML][HTML] Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults

…, RA Kronmal, TA Manolio, GL Burke… - … England Journal of …, 1999 - Mass Medical Soc
Background The combined thickness of the intima and media of the carotid artery is associated
with the prevalence of cardiovascular disease. We studied the associations between the …

Risk factors for dementia in the cardiovascular health cognition study

…, OL Lopez, A Newman, NJ Beauchamp, G Burke… - …, 2003 - karger.com
Background: The Cardiovascular Health Cognition Study has evaluated the determinants of
dementia among 3,608 participants that had a magnetic resonance imaging (MRI) of the …

Multi-ethnic study of atherosclerosis: objectives and design

DE Bild, DA Bluemke, GL Burke… - American journal of …, 2002 - academic.oup.com
The Multi-Ethnic Study of Atherosclerosis was initiated in July 2000 to investigate the prevalence,
correlates, and progression of subclinical cardiovascular disease (CVD) in a population…

Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association

SM Grundy, IJ Benjamin, GL Burke, A Chait, RH Eckel… - Circulation, 1999 - Am Heart Assoc
This statement examines the cardiovascular complications of diabetes mellitus and considers
opportunities for their prevention. These complications include coronary heart disease (…

[HTML][HTML] Coronary calcium as a predictor of coronary events in four racial or ethnic groups

…, AD Guerci, JJ Carr, DE Bild, G Burke… - … England Journal of …, 2008 - Mass Medical Soc
Background In white populations, computed tomographic measurements of coronary-artery
calcium predict coronary heart disease independently of traditional coronary risk factors. …