User profiles for H Hirano

Hiroyuki Hirano

The University of Tokyo
Verified email at g.ecc.u-tokyo.ac.jp
Cited by 8080

Genetics and evolution of inflorescence and flower development in grasses

…, D Jackson, HY Hirano - Plant and Cell …, 2005 - academic.oup.com
… Research on flower development in the Hirano laboratory is partly supported by Grants-in-Aid
for Scientific Research (15031208) from the Ministry of Education, Culture, Sports, Science …

Sarcopenia: Prevalence and associated factors based on different suggested definitions in community‐dwelling older adults

H Kim, H Hirano, A Edahiro, Y Ohara… - Geriatrics & …, 2016 - Wiley Online Library
The age‐related loss of muscle mass and/or strength and performance, sarcopenia, has
been associated with geriatric syndromes, morbidity and mortality. Although sarcopenia has …

Grass meristems II: inflorescence architecture, flower development and meristem fate

…, M Pautler, D Jackson, HY Hirano - Plant and Cell …, 2013 - academic.oup.com
Plant development depends on the activity of various types of meristems that generate organs
such as leaves and floral organs throughout the life cycle. Grass species produce complex …

[HTML][HTML] Gefitinib or chemotherapy for non–small-cell lung cancer with mutated EGFR

…, I Kinoshita, Y Fujita, S Okinaga, H Hirano… - … England Journal of …, 2010 - Mass Medical Soc
Background Non–small-cell lung cancer with sensitive mutations of the epidermal growth
factor receptor (EGFR) is highly responsive to EGFR tyrosine kinase inhibitors such as gefitinib…

Observation of Large Violation in the Neutral Meson System

…, Y Higasino, I Higuchi, T Higuchi, T Hirai, H Hirano… - Physical review …, 2001 - APS
We present a measurement of the standard model CP violation parameter sin 2 φ 1 based
on a 29.1 fb− 1 data sample collected at the ϒ (4 S) resonance with the Belle detector at the …

Engineered CRISPR-Cas9 nuclease with expanded targeting space

…, B Holmes, M Tanaka, M Seki, H Hirano, H Aburatani… - Science, 2018 - science.org
The RNA-guided endonuclease Cas9 cleaves its target DNA and is a powerful genome-editing
tool. However, the widely used Streptococcus pyogenes Cas9 enzyme (SpCas9) …

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

Y Tanaka, DH Adams, S Hubscher, H Hirano… - Nature, 1993 - nature.com
LYMPHOCYTE migration from blood into tissue depends on integrin-mediated adhesion to
endothelium 1–4 . Adhesion requires not only integrin ligands on the endothelium, but also …

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme

…, M Kochi, H Nakamura, K Makino, H Saya, H Hirano… - Cancer research, 2003 - AACR
Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the
epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied mutations, …

[HTML][HTML] Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin–paclitaxel for chemo-naïve non-small cell lung cancer …

…, I Kinoshita, Y Fujita, S Okinaga, H Hirano… - Annals of oncology, 2013 - Elsevier
Background NEJ002 study, comparing gefitinib with carboplatin (CBDCA) and paclitaxel (PTX;
Taxol) as the first-line treatment for advanced non-small cell lung cancer (NSCLC) …

Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation …

M Takakura, S Kyo, T Kanaya, H Hirano, J Takeda… - Cancer research, 1999 - AACR
… vector (Promega) for 5 h at 37C. Then, 3 ml of growth media were added to the cells, followed
by incubation for an additional 16 h. The cells were harvested 48 h after the transfection. …