Background In 2010, overweight and obesity were estimated to cause 3·4 million deaths, 3·9%
of years of life lost, and 3·8% of disability-adjusted life-years (DALYs) worldwide. The rise …

Using a yeast interaction screen to search for proteins that interact with cyclin Dl-Cdk4, we
identified a 27 kDa mouse protein related to the p21 cyclin-Cdk inhibitor. p27 interacts …

Insulin resistance is often associated with obesity and can precipitate type 2 diabetes. To
date, most known approaches that improve insulin resistance must be preceded by the …

… , mice were fasted for 24 h and then fed a high-sucrose/fat-free diet for 12 h, as previously
… weeks to induce transgene expression and then fasted for 12 h before sacrifice 25,26 . ob/+ …

Human cDNA clones encoding four novel putative transmembrane protein serine/threonine
kinases, denoted activin receptor-like kinase (ALK)-1,-2,-3 and-4, were obtained using a …

… After soaking for 3 h and gaseous treatment for 21 h at 35 C, the content of γ-aminobutyric
acid (GABA) in GBR (24.9 mg/100 g) was higher than that by the conventional soaking method …

OBJECTIVE: To elucidate the underlying mechanisms between C-reactive protein (CRP)
and cardiovascular disease, we exa-mined the association of circulating CRP in healthy …

BACKGROUND: Few epidemiologic studies have examined the association between the
rate of eating and obesity. In this study, we cross-sectionally examined the association of the …

Background— Perceived mental stress has been associated with risk of coronary heart
disease (CHD) in white men, but no prospective data are available for other ethnic groups. …

… We excluded 6946 subjects for whom demographic, socioeconomic, or dietary information
was missing or who had fasted <6 h before venipuncture and 195 women who were pregnant …