A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer

HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
Introduction Patients with non-small cell lung cancer (NSCLC) harboring uncommon
epidermal growth factor receptor (EGFR) mutations are a heterogeneous group exhibiting …

TianQin: a space-borne gravitational wave detector

…, M Sazhin, CG Shao, VT Toth, HB Tu… - … and Quantum Gravity, 2016 - iopscience.iop.org
TianQin is a proposal for a space-borne detector of gravitational waves in the millihertz
frequencies. The experiment relies on a constellation of three drag-free spacecraft orbiting the …

Recent advances in nickel-catalyzed three-component difunctionalization of unactivated alkenes

HY Tu, S Zhu, FL Qing, L Chu - Synthesis, 2020 - thieme-connect.com
Catalytic, intermolecular difunctionalization of alkenes represents an efficient and diverse
protocol for the buildup of molecular complexity from abundant materials by forging two …

Potential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung Adenocarcinoma

…, WZ Zhong, XC Zhang, J Su, Z Xie, SY Liu, HY Tu… - Clinical cancer …, 2017 - AACR
Purpose: Although clinical studies have shown promise for targeting programmed cell death
protein-1 (PD-1) and ligand (PD-L1) signaling in non–small cell lung cancer (NSCLC), the …

The development of carbon dots: From the perspective of materials chemistry

…, H Tu, H Zhang, DS Silvester, CE Banks, G Zou, H Hou… - Materials Today, 2021 - Elsevier
… Surface functionalization is generally related with covalently bonded functional groups (containing
O and H that saturate the dangling bonds in N, S, B etc.) on carbon basal surfaces or …

EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancer

…, SY Liu, J Su, C Zhang, Z Xie, Q Zhou, HY Tu… - …, 2017 - Taylor & Francis
Patients with EGFR mutations showed unfavorable response to programmed cell death-1 (PD-1)
blockade immunotherapy in non-small cell lung cancer (NSCLC). Yet the underlying …

Longitudinal undetectable molecular residual disease defines potentially cured population in localized non–small cell lung cancer

…, S Dong, Y Guan, P Dai, XC Zhang, JJ Yang, HY Tu… - Cancer Discovery, 2022 - AACR
This study confirms the prognostic value of MRD detection in patients with NSCLC after definitive
surgery, especially in those with longitudinal undetectable MRD, which might represent …

[HTML][HTML] Nivolumab versus docetaxel in a predominantly Chinese patient population with previously treated advanced NSCLC: CheckMate 078 randomized phase III …

…, C Zhou, J Wang, T Mok, L Zhang, HY Tu… - Journal of Thoracic …, 2019 - Elsevier
Introduction Data on immuno-oncology agents in Chinese patients are limited despite a need
for new therapies. We evaluated the efficacy and safety of nivolumab in a predominantly …

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

…, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu… - Cancer discovery, 2020 - AACR
T-DM1 is clinically effective in lung cancers with amplification of or mutations in ERBB2 . This
activity is enhanced by cotreatment with irreversible pan-HER inhibitors, or ADC switching …

Enantioselective three-component fluoroalkylarylation of unactivated olefins through nickel-catalyzed cross-electrophile coupling

HY Tu, F Wang, L Huo, Y Li, S Zhu, X Zhao… - Journal of the …, 2020 - ACS Publications
A nickel-catalyzed, enantioselective, three-component fluoroalkylarylation of unactivated
alkenes with aryl halides and perfluoroalkyl iodides has been described. This cross-…