A phase II trial of tideglusib in Alzheimer's disease

…, M Hüll, JO Rinne, HJ Huppertz… - Journal of …, 2015 - content.iospress.com
Background: The ARGO study was a phase II, double-blind, placebo controlled, four parallel
arm trial of tideglusib in Alzheimer’s disease (AD). Objective: To prove the clinical efficacy of …

Enhanced visualization of blurred gray–white matter junctions in focal cortical dysplasia by voxel-based 3D MRI analysis

HJ Huppertz, C Grimm, S Fauser, J Kassubek, I Mader… - Epilepsy research, 2005 - Elsevier
PURPOSE: Focal cortical dysplasia (FCD), a frequent cause of partial epilepsy, is often
associated with blurring of the gray–white matter junction in magnetic resonance images (MRI). …

Focal cortical dysplasias: surgical outcome in 67 patients in relation to histological subtypes and dual pathology

…, J Honegger, H Carmona, HJ Huppertz… - Brain, 2004 - academic.oup.com
The purpose of this study was to assess whether the histological subtype of focal cortical
dysplasia and dual pathology affect surgical outcome in patients with medically intractable …

Transvenous treatment of carotid cavernous and dural arteriovenous fistulae: results for 31 patients and review of the literature

J Klisch, HJ Huppertz, U Spetzger, A Hetzel… - …, 2003 - journals.lww.com
OBJECTIVE: To evaluate findings for patients with carotid cavernous fistulae or dural
arteriovenous fistulae (AVFs) who underwent transvenous embolization via different transvenous …

Clinical characteristics in focal cortical dysplasia: a retrospective evaluation in a series of 120 patients

S Fauser, HJ Huppertz, T Bast, K Strobl, G Pantazis… - Brain, 2006 - academic.oup.com
Focal cortical dysplasias (FCDs) are increasingly diagnosed as a cause of symptomatic
focal epilepsy in paediatric and adult patients. However, little is known about the clinical …

Morphometric MRI analysis improves detection of focal cortical dysplasia type II

J Wagner, B Weber, H Urbach, CE Elger, HJ Huppertz - Brain, 2011 - academic.oup.com
Focal cortical dysplasias type II (FCD II) are highly epileptogenic lesions frequently causing
pharmacoresistant epilepsy. Detection of these lesions on MRI is still challenging as FCDs …

Global brain atrophy and corticospinal tract alterations in ALS, as investigated by voxel‐based morphometry of 3‐D MRI

J Kassubek, A Unrath, HJ Huppertz, D Lulé… - Amyotrophic Lateral …, 2005 - Taylor & Francis
In ALS, advanced magnetic resonance imaging (MRI) techniques are increasingly used to
investigate the underlying pathology. In this study, the technique of voxel‐based morphometry …

A voxel-based morphometric MRI study in female patients with borderline personality disorder

…, LT Van Elst, P Ludaescher, M Wilke, HJ Huppertz… - Neuroimage, 2003 - Elsevier
Subtle prefrontal and limbic structural abnormalities have been reported in borderline personality
disorder (BPD). In order to further validate the previously reported findings and to more …

Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial

GU Höglinger, HJ Huppertz, S Wagenpfeil… - Movement …, 2014 - Wiley Online Library
Huppertz received honoraria for scientific presentations from UCB and research support
from the Swiss Epilepsy Foundation (Swiss EPI) and the Swiss National Science Foundation (…

Intra-and interscanner variability of automated voxel-based volumetry based on a 3D probabilistic atlas of human cerebral structures

HJ Huppertz, J Kröll-Seger, S Klöppel, RE Ganz… - Neuroimage, 2010 - Elsevier
The intra- and inter-scanner variability of an automated method for MRI-based volumetry
was investigated. Using SPM5 algorithms and predefined masks derived from a probabilistic …