High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor
…, SGF Rasmussen, FS Thian, TS Kobilka, HJ Choi… - science, 2007 - science.org
Heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors constitute
the largest family of eukaryotic signal transduction proteins that communicate across the …
the largest family of eukaryotic signal transduction proteins that communicate across the …
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
SGF Rasmussen, HJ Choi, DM Rosenbaum… - Nature, 2007 - nature.com
Structural analysis of G-protein-coupled receptors (GPCRs) for hormones and neurotransmitters
has been hindered by their low natural abundance, inherent structural flexibility, and …
has been hindered by their low natural abundance, inherent structural flexibility, and …
Factors influencing adult learners' decision to drop out or persist in online learning
The number of adult learners who participate in online learning has rapidly grown in the last
two decades due to online learning’s many advantages. In spite of the growth, the high …
two decades due to online learning’s many advantages. In spite of the growth, the high …
The origin of the anomalous superconducting properties of MgB2
Magnesium diboride 1 differs from ordinary metallic superconductors in several important
ways, including the failure of conventional models 2 to predict accurately its unusually high …
ways, including the failure of conventional models 2 to predict accurately its unusually high …
Metal-free catalysts for oxygen reduction reaction
The rising global energy demand and environmental impact of traditional energy resources
pose serious challenges to human health, energy security, and environmental protection.(1-3…
pose serious challenges to human health, energy security, and environmental protection.(1-3…
Controlled growth of ZnO nanowires and their optical properties
This article surveys recent developments in the rational synthesis of single‐crystalline zinc
oxide nanowires and their unique optical properties. The growth of ZnO nanowires was …
oxide nanowires and their unique optical properties. The growth of ZnO nanowires was …
Single-crystal gallium nitride nanotubes
Since the discovery of carbon nanotubes in 1991 (ref. 1 ), there have been significant research
efforts to synthesize nanometre-scale tubular forms of various solids 2 , 3 , 4 , 5 , 6 , 7 , 8 , …
efforts to synthesize nanometre-scale tubular forms of various solids 2 , 3 , 4 , 5 , 6 , 7 , 8 , …
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy
Owing to its high carrier mobility, conductivity, flexibility and optical transparency, graphene
is a versatile material in micro-and macroelectronics. However, the low density of …
is a versatile material in micro-and macroelectronics. However, the low density of …
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon… - Nature, 2011 - nature.com
G protein coupled receptors (GPCRs) exhibit a spectrum of functional behaviours in response
to natural and synthetic ligands. Recent crystal structures provide insights into inactive …
to natural and synthetic ligands. Recent crystal structures provide insights into inactive …
Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer …
…, X Chen, A Cheng, TJ Chiu, HJ Choi, HJ Chon… - The Lancet, 2023 - thelancet.com
Background Biliary tract cancers, which arise from the intrahepatic or extrahepatic bile ducts
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide. …
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide. …
