Background and Purpose— This study evaluated the safety and efficacy of aggressive
mechanical clot disruption (AMCD) in acute stroke patients with persisting middle cerebral artery (…

Background and Purpose— The optimal approach for acute ischemic stroke patients who do
not respond to intravenous recombinant tissue plasminogen activator (IV rt-PA) is uncertain. …

Background and Purpose— Studies have established a relation between recanalization and
improved clinical outcome in acute ischemic stroke patients; however, intra-arterial clot size …

BACKGROUND: The use of flow diverters such as the pipeline embolization device (PED)
for treatment of intracranial aneurysms carries the risk of side branch occlusion. OBJECTIVE: …

“Silent strokes” or “subclinical strokes” refer to incidental findings of strokes on
neuroimaging studies, such as computed tomography or magnetic resonance imaging/diffusion-weighted …

Background The benefit of intravenous recombinant tissue plasminogen activator (rtPA) in
acute stroke is linked to clot lysis and artery recanalization. Argatroban is a direct thrombin …

Introduction Penetrating gunshot injuries (GSI) to supra-aortic arteries that cause life-threatening
blood loss or major neurologic deficits are increasingly managed using modern …

Objective: Coexistence of both an intracranial aneurysm and a stenosis at the same internal
carotid artery is infrequent, but it may complicate therapeutic management of either disease. …

BACKGROUND AND PURPOSE: Reteplase (RP) and urokinase (UK) are being used “off-label”
to treat acute ischemic stroke. The safety and efficacy of intra-arterial RP or UK in the …

BACKGROUND: Endovascular therapy (ET) of internal carotid artery (ICA) stenosis is
equivalent to carotid endarterectomy for stroke prevention; however, patients with ICA occlusion …