Quantitative Gd‐DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA‐SPGR at 9.4 T

H Lee, K Mortensen, S Sanggaard… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose We propose a quantitative technique to assess solute uptake into the brain
parenchyma based on dynamic contrast‐enhanced MRI (DCE‐MRI). With this approach, a small …

[HTML][HTML] Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

JJ Iliff, H Lee, M Yu, T Feng, J Logan… - The Journal of …, 2013 - Am Soc Clin Investig
The glymphatic system is a recently defined brain-wide paravascular pathway for cerebrospinal
fluid (CSF) and interstitial fluid (ISF) exchange that facilitates efficient clearance of …

Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport

V Ratner, Y Gao, H Lee, R Elkin, M Nedergaard… - Neuroimage, 2017 - Elsevier
The glymphatic pathway is a system which facilitates continuous cerebrospinal fluid (CSF)
and interstitial fluid (ISF) exchange and plays a key role in removing waste products from the …

Perivascular spaces in the brain: anatomy, physiology and pathology

…, M Nedergaard, BV Zlokovic, H Mestre, H Lee… - Nature Reviews …, 2020 - nature.com
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

The effect of body posture on brain glymphatic transport

H Lee, L Xie, M Yu, H Kang, T Feng… - Journal of …, 2015 - Soc Neuroscience
The glymphatic pathway expedites clearance of waste, including soluble amyloid β (Aβ) from
the brain. Transport through this pathway is controlled by the brain9s arousal level because…

The glymphatic system and waste clearance with brain aging: a review

H Benveniste, X Liu, S Koundal, S Sanggaard, H Lee… - Gerontology, 2019 - karger.com
The glymphatic system is a glial-dependent waste clearance pathway in the brain, in place
of lymphatic vessels, dedicated to drain away soluble waste proteins and metabolic products. …

Neural correlates of emotion processing in borderline personality disorder

HW Koenigsberg, LJ Siever, H Lee, S Pizzarello… - Psychiatry Research …, 2009 - Elsevier
Emotional instability is a hallmark feature of borderline personality disorder (BPD), yet its
biological underpinnings are poorly understood. We employed functional magnetic resonance …

Cerebrovascular effects of hemodialysis in chronic kidney disease

I Prohovnik, J Post, J Uribarri, H Lee… - Journal of Cerebral …, 2007 - journals.sagepub.com
Patients with end-stage renal disease (ESRD) undergoing hemodialysis are known to suffer
cognitive deficits and stroke of unknown etiology. It has been suspected that the treatment …

The glymphatic pathway: waste removal from the CNS via cerebrospinal fluid transport

H Benveniste, H Lee, ND Volkow - The Neuroscientist, 2017 - journals.sagepub.com
The overall premise of this review is that cerebrospinal fluid (CSF) is transported within a
dedicated peri-vascular network facilitating metabolic waste clearance from the central nervous …

Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose …

H Benveniste, H Lee, F Ding, Q Sun, E Al-Bizri… - …, 2017 - pubs.asahq.org
Background The glymphatic pathway transports cerebrospinal fluid through the brain, thereby
facilitating waste removal. A unique aspect of this pathway is that its function depends on …