Comparison of fluorotyrosines and methionine uptake in F98 rat gliomas

KJ Langen, M Jarosch, H Mühlensiepen… - Nuclear medicine and …, 2003 - Elsevier
The transport mechanisms of O-(2-[ 18 F]fluoroethyl)-L-tyrosine (FET) and 2-[ 18 F]fluoro-L-tyrosine
(FTyr) were compared to those of [ 3 H]-Methyl-L-methionine (MET) in F98 rat glioma …

Uptake kinetics of the somatostatin receptor ligand [86Y]DOTA-dPhe1-Tyr3-octreotide ([86Y]SMT487) using positron emission tomography in non-human primates and …

…, J Brockmann, M Köhle, H Mühlensiepen… - European journal of …, 1999 - Springer
[ 90 Y]DOTA-dPhe 1 -Tyr 3 -octreotide ([ 90 Y]-SMT487) has been suggested as a promising
radiotherapeutic agent for somatostatin receptor-expressing tumours. In order to quantify …

[PDF][PDF] Transport mechanisms of 3-[123I] iodo-α-methyl-L-tyrosine in a human glioma cell line: comparison with [3H-methyl]-L-methionine

KJ Langen, H Mühlensiepen… - Journal of nuclear …, 2000 - Soc Nuclear Med
The amino acid analog 3-[123l] iodo-a-methyl-i_-tyrosine (IMT) is under clinical evaluation
as a SPECT tracer of amino acid transport in brain tumors. This study investigated the carrier …

Transport of cis-and trans-4-[18F] fluoro-L-proline in F98 glioma cells

KJ Langen, H Mühlensiepen, S Schmieder… - Nuclear medicine and …, 2002 - Elsevier
The transport mechanisms of cis-4-[ 18 F]fluoro-L-proline (cis-FPro) and trans-4-[ 18 F]fluoro-L-proline
(trans-FPro) were studied in F98 rat glioma cells in comparison to the natural …

Imaging of gliomas with Cis-4-[18F] fluoro-L-proline

…, M Jarosch, K Hamacher, H Mühlensiepen… - Nuclear medicine and …, 2004 - Elsevier
Tumor imaging with cis-4-[ 18 F]fluoro-L-proline (cis-FPro) was compared to that of L-[ 3 H]proline
and L-[ 3 H]methionine in F98 rat gliomas by dual-tracer autoradiography. All tracers …

3-[123I] iodo-α-methyl-l-tyrosine transport and 4F2 antigen expression in human glioma cells

KJ Langen, R Bonnie, H Mühlensiepen… - Nuclear medicine and …, 2001 - Elsevier
3[ 123 I]iodo-α-methyl-L-tyrosine is a tracer of amino acid transport in brain tumors using
single-photon emission-computed tomography and predominantly transported by amino acid …

[PDF][PDF] A cell-culture reactor for the on-line evaluation of radiopharmaceuticals: evaluation of the lumped constant of FDG in human glioma cells

T Noll, H Mühlensiepen, R Engels… - Journal of nuclear …, 2000 - Soc Nuclear Med
S-phase portionof 25% — 40%. For furtherexaminationof the cells, an enzymatic method for
detachment from the carriers without cellular destruction was introduced. In the FDG experi …

[PDF][PDF] Transport Mechanisms of 3-[123I] Iodo-a-Methyl-L-Tyrosine in a Human Glioma Cell Line: Comparison with [3H-methy 1]-L-Methionine

KJ Langen, H Muhlensiepen, M Holschbach… - Age (Omaha …, 2000 - scholar.archive.org
The amino acid analog 3-[123l] iodo-a-methyl-i_-tyrosine (IMT) is under clinical evaluation
as a SPECT tracer of amino acid transport in brain tumors. This study investigated the carrier …

Effects of varenicline on alpha4-containing nicotinic acetylcholine receptor expression and cognitive performance in mice

C Lange-Asschenfeldt, S Schäble, T Suvorava… - …, 2016 - Elsevier
Nicotinic acetylcholine receptor (nAChR) subtypes containing the α 4 subunit, particularly α
4 β 2 nAChRs, play an important role in cognitive functioning. The impact of the smoking …

Comparison of iodotyrosines and methionine uptake in a rat glioma model

KJ Langen, RP Clauss, M Holschbach… - The Journal of …, 1998 - search.proquest.com
This study compares brain tumor imaging with 3-[123I] iodo-alpha-methyl-L-tyrosine (IMT)
and 3-[123I/125I] iodo-O-methyl-alpha-methyl-L-tyrosine (OMIMT) to that with [methyl-3H]-L-…