PURPOSE: To assess change in incidence of retinoblastoma in Northern Europe and to
compare commonly used methods for calculating its incidence against birth cohort analysis. …

BACKGROUND AND PURPOSE: The possible relationship of orbit deformities in neurofibromatosis
type 1 (NF1) to plexiform neurofibromas (PNFs) have not been fully elucidated. Our …

BACKGROUND AND PURPOSE: Sphenoid dysplasia associated with neurofibromatosis
type 1 is classically thought to be primarily related to abnormal development of the sphenoid …

Purpose To study the tolerability of the ICare rebound tonometer (RBT) and to establish
reference values of the intraocular pressure (IOP) in healthy infants. Participants and Methods …

Background Excimer laser refractive surgery alters the shape and thickness of the cornea by
removing central corneal tissue with submicrometer precision. The aim of the study was to …

The Wilms tumor gene (WT1) encodes a zinc-finger containing transcription factor present
in primitive hematopoietic progenitor cells. WT1 is also highly expressed in most cases of …

The Wilms tumor gene, WT1, encodes a zinc-finger DNA binding protein which is thought to
function as a tissue specific transcription factor, regulating cell growth and differentiation. …

The tumor suppressor gene p53 can mediate both apoptosis and cell cycle arrest. In addition,
p53 also influences differentiation. To further characterize the differentiation inducing …

The p53 tumor suppressor protein can induce both apoptosis and cell cycle arrest. Moreover,
we and others have shown previously that p53 is a potent mediator of differentiation. For …

The Wilms’ tumor gene (WT1) encodes a transcription factor of the zinc finger type. A high
expression of WT1 has been detected in a range of acute leukemias, and WT1 is …