A sensitive immunohistochemical method for phosphorylated α-synuclein was used to stain
sets of sections of spinal cord and tissue from 41 different sites in the bodies of 92 subjects, …

The two current major staging systems in use for Lewy body disorders fail to classify up to 50%
of subjects. Both systems do not allow for large numbers of subjects who have Lewy-type …

Our purpose was to characterize a state of mild cognitive impairment (MCI) in Parkinson's
disease (PD) (PD‐MCI) that would be analogous to the MCI that is posited as a precursor of …

Objectives: Determine diagnostic accuracy of a clinical diagnosis of Parkinson disease (PD)
using neuropathologic diagnosis as the gold standard. Methods: Data from the Arizona …

The B rain and B ody D onation P rogram ( BBDP ) at B anner S un H ealth R esearch I
nstitute ( http://www.brainandbodydonationprogram.org ) started in 1987 with brain‐only …

Aims: To perform an item analysis of the Montreal Cognitive Assessment (MoCA) versus the
Mini-Mental State Examination (MMSE) in the prediction of cognitive impairment, and to …

Importance Coenzyme Q10 (CoQ10), an antioxidant that supports mitochondrial function, has
been shown in preclinical Parkinson disease (PD) models to reduce the loss of dopamine …

Involvement of the olfactory bulb by Lewy-type α-synucleinopathy (LTS) is known to occur at
an early stage of Parkinson’s disease (PD) and Lewy body disorders and is therefore of …

Subjects with Parkinson disease (PD) frequently develop dementia with greater than one-third
meeting neuropathologic diagnostic criteria for Alzheimer disease (AD). The objective is …

Importance Urate elevation, despite associations with crystallopathic, cardiovascular, and
metabolic disorders, has been pursued as a potential disease-modifying strategy for …