A characteristic of nerve cells is their ability to propagate an action potential and to communicate
through specialized contact zones, called synapses. Synapses have received much …

Epilepsy is the tendency to have unprovoked epileptic seizures. Anything causing structural
or functional derangement of brain physiology may lead to seizures, and different conditions …

One century ago, Camillo Golgi described ‘perineuronal nets’ enwrapping the cell bodies and
proximal dendrites of certain neurons in the adult mammalian central nervous system and …

Purpose: Focal cortical dysplasias (FCD) are localized regions of malformed cerebral cortex
and are very frequently associated with epilepsy in both children and adults. A broad …

Hippocampal sclerosis ( HS ) is the most frequent histopathology encountered in patients
with drug‐resistant temporal lobe epilepsy ( TLE ). Over the past decades, various attempts …

Background Detailed neuropathological information on the structural brain lesions underlying
seizures is valuable for understanding drug-resistant focal epilepsy. Methods We report …

Purpose: To describe the histologic spectrum and clinical characteristics of patients with
neuroepithelial tumors and drug‐resistant epilepsy and to analyze clinical data and treatment …

Proximal spinal muscular atrophy (SMA) is a common neuromuscular disorder causing
infant death in half of all patients. Homozygous absence of the survival motor neuron gene ( …

We propose a histopathological classification system for hippocampal cell loss in patients
suffering from mesial temporal lobe epilepsies (MTLE). One hundred and seventy-eight …

Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous
research and consensus agreement to improve disease definition and classification. An …