Aptamers as therapeutics

AD Keefe, S Pai, A Ellington - Nature reviews Drug discovery, 2010 - nature.com
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to
bind a wide range of biomedically relevant proteins with affinities and specificities that are …

Systematic review: T-cell–based assays for the diagnosis of latent tuberculosis infection: an update

M Pai, A Zwerling, D Menzies - Annals of internal medicine, 2008 - acpjournals.org
Background: Interferon-γ–release assays (IGRAs) are alternatives to the tuberculin skin test (TST).
A recent meta-analysis showed that IGRAs have high specificity, even among …

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults

KR Steingart, I Schiller, DJ Horne, M Pai… - Cochrane database …, 2014 - cochranelibrary.com
Background Accurate, rapid detection of tuberculosis (TB) and TB drug resistance is critical
for improving patient care and decreasing TB transmission. Xpert® MTB/RIF assay is an …

Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

…, M Lussier, N M'Rabet, P Menard, M Mittmann, C Pai… - science, 1999 - science.org
The functions of many open reading frames (ORFs) identified in genome-sequencing projects
are unknown. New, whole-genome approaches are required to systematically determine …

[HTML][HTML] The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines

…, OJ Muensterer, PJ Bradley, P Goel, PS Pai… - International Journal of …, 2020 - Elsevier
Introduction The SCARE Guidelines were first published in 2016 and were last updated in
2018. They provide a structure for reporting surgical case reports and are used and endorsed …

Strong association of de novo copy number mutations with autism

…, S Yoon, A Krasnitz, J Kendall, A Leotta, D Pai… - Science, 2007 - science.org
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …

Bloom: A 176b-parameter open-access multilingual language model

…, S Sharma, S Longpre, S Nikpoor, S Silberberg, S Pai… - 2023 - inria.hal.science
Large language models (LLMs) have been shown to be able to perform new tasks based on
a few demonstrations or natural language instructions. While these capabilities have led to …

[BOOK][B] Energy function analysis for power system stability

A Pai - 1989 - books.google.com
This research monograph is in some sense a sequel to the author's earlier one (Power
System Stability, North Holland, New York 1981) which devoted cons-erable attention to …

Spin-torque switching with the giant spin Hall effect of tantalum

L Liu, CF Pai, Y Li, HW Tseng, DC Ralph, RA Buhrman - Science, 2012 - science.org
Spin currents can apply useful torques in spintronic devices. The spin Hall effect has been
proposed as a source of spin current, but its modest strength has limited its usefulness. We …

[BOOK][B] Power system dynamics and stability: with synchrophasor measurement and power system toolbox

PW Sauer, MA Pai, JH Chow - 2017 - books.google.com
Classic power system dynamics text now with phasor measurement and simulation toolbox
This new edition addresses the needs of dynamic modeling and simulation relevant to power …