ObjectiveBecause of the pressure for timely, informed decisions in public health and clinical
practice and the explosion of information in the scientific literature, research results must be …

Background The Quality of Reporting of Meta-analyses (QUOROM) conference was convened
to address standards for improving the quality of reporting of meta-analyses of clinical …

▪ Abstract This review is divided into two parts, the first dealing with the cell and molecular
biology of muscle in terms of growth and wasting and the second being an account of current …

Medical practice is constantly changing. The rate of change is accelerating, and physicians
can be forgiven if they often find it dizzying. How can physicians learn about new information …

The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting,
and appraisal. However, trial protocols and existing protocol guidelines vary greatly in …

The rewards and dangers of speculating in the modern financial markets have come to the
fore in recent times with the collapse of banks and bankruptcies of public corporations as a …

Background To comprehend the results of diagnostic accuracy studies, readers must understand
the design, conduct, analysis, and results of such studies. That goal can be achieved …

THE RANDOMIZED controlled trial (RCT), more than any other methodology, can have a
powerful and immediate impact on patient care. Ideally, the report of such an evaluation needs …

Incomplete reporting has been identified as a major source of avoidable waste in biomedical
research. Essential information is often not provided in study reports, impeding the …

We present a set of evolving guidelines for reviewing qualitative research, to serve four
functions: to contribute to the process of legitimizing qualitative research; to ensure more …