OBJECTIVE: The Department of Medical Imaging at the University Health Network in Toronto
is performing a lung cancer screening study, utilizing low-dose computed tomography (…

Purpose: Interstitial fluid pressure (IFP) and oxygen (pO 2 ) measurements are prognostic
factors in cervical cancer. The purpose of this study was to determine the relationship between …

Objective: To evaluate computed tomography (CT) perfusion using first pass methods for
lung nodule characterization. Methods: Fifty-seven patients with 51 malignant and 6 benign …

Purpose To correlate permeability (rk trans ), extracellular volume fraction (rv e ), relative to
muscle and initial area under the enhancement curve (IAUC 60m ) determined by dynamic …

BACKGROUND AND PURPOSE: Secondary-progressive MS is characterized by reduced
acute inflammation and contrast enhancement but with increased axonal degeneration and …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
results in demyelination, destruction of oligodendricytes, and, eventually, long-term …

Glioblastoma multiforme (GBM) is the most common primary brain tumor and has a very
poor prognosis. Treatment assessment is difficult as early imaging changes cannot be easily …

Hemorrhagic transformation (HT) is a major adverse outcome of acute ischemic stroke.
Accurate methods for predicting HT would improve patient care and stratify risk when directing …

… We read with great interest the article by Sitartchouk et al1 in the June 2008 issue of
Investigative Radiology, and we appreciated the authors’ work to propose this technique as a …

… The study of Sitartchouk et al is conducted on a small number of patients with benign nodules,
but inflammatory lesions are not included. Because inflammatory lesions are associated …