… Alternatively, these patterns may represent different immune responses across individuals
or different lesion types (ie, nodular lesions may be newly forming, whereas ringlike lesions …

… ) score 17 between 0 and 6.5; and treatment with interferon beta (either 1a or 1b) at fully
tolerated dose for at least 6 months before enrollment and with evidence of clinical efficacy (ie, …

… lesions and the contralateral NAWM by drawing the same size of region of interest on the
parametric images where V T /f P values were calculated in each voxel using the Logan plot (ie…

BACKGROUND AND PURPOSE: Several studies suggest that grey matter involvement may
play a role in multiple sclerosis (MS) pathology. Diffusion tensor imaging (DTI) at 3T was …

… Additionally, we amended our original protocol in 2013 to include serial fetal MR imaging
studies (ie, 2 fetal MR imaging studies) as part of this prospective study, to examine fetal brain …

… Initially to avoid over-controlling (ie, removing effects that might be part of a causal chain
between CHD and CBF), we adjusted only for differences in GA. Subsequently, we evaluated …

… However, brain MRI indices derived from conventional techniques (ie, lesion volume and
atrophy) only moderately explain physical disability of MS patients.2 To fill the gap in the …

BACKGROUND AND PURPOSE: 1 H-MRS provides a noninvasive way to study fetal brain
maturation at the biochemical level. The purpose of this study was to characterize in vivo …

… data that include independently moving objects (ie, the placenta and fetal brain) and are
acquired with the epoch-based paradigm of sequential block design (ie, short-term maternal …

… Similarly, others reported no differences in focal WM MS disease (ie, T 2 WM-lesion load […
(ie, 3.0 Tesla [3T]). We measured quantity, (ie, volume of lesions and of NAWM) and quality (ie, …